Pathogenesis of antiphospholipid syndrome: understanding the antibodies

PL Meroni, MO Borghi, E Raschi… - Nature Reviews …, 2011 - nature.com
Antiphospholipid antibodies (aPL) are both diagnostic markers for, and pathogenic drivers
of, antiphospholipid syndrome (APS). Although the presence of aPL is a necessary pre …

Lupus vasculitis: an overview

P Leone, M Prete, E Malerba, A Bray, N Susca… - Biomedicines, 2021 - mdpi.com
Lupus vasculitis (LV) is one of the secondary vasculitides occurring in the setting of systemic
lupus erythematosus (SLE) in approximately 50% of patients. It is most commonly …

Autoimmunity and pulmonary hypertension: a perspective

MR Nicolls, L Taraseviciene-Stewart… - European …, 2005 - Eur Respiratory Soc
The association between autoimmunity and pulmonary arterial hypertension (PAH) has
been appreciated for> 40 yrs, but how autoimmune injury might contribute to the …

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

F Shimizu, KL Schaller, GP Owens… - Science translational …, 2017 - science.org
Neuromyelitis optica (NMO) is an inflammatory disorder mediated by antibodies to
aquaporin-4 (AQP4) with prominent blood-brain barrier (BBB) breakdown in the acute phase …

Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE

JH Ju, JK Min, CK Jung, SN Oh, SK Kwok… - Nature Reviews …, 2009 - nature.com
Lupus mesenteric vasculitis (LMV) is a unique clinical entity found in patients who present
with gastrointestinal manifestations of systemic lupus erythematosus, and is the main cause …

Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling

L Taraseviciene-Stewart, MR Nicolls… - American journal of …, 2007 - atsjournals.org
Rationale: Severe pulmonary arterial hypertension (SPH) is a frequently lethal condition
characterized by pulmonary vascular remodeling and right heart strain or failure. SPH is also …

Oxidative stress in the pathogenesis of systemic scleroderma: An overview

R Vona, A Giovannetti, L Gambardella… - Journal of Cellular …, 2018 - Wiley Online Library
Systemic sclerosis (SS c) is a rare disorder of the connective tissue characterized by fibrosis
of the skin, skeletal muscles and visceral organs. Additional manifestations include …

Renal microvascular lesions in lupus nephritis

Y Ding, Y Tan, Z Qu, F Yu - Renal failure, 2020 - Taylor & Francis
Renal microvascular lesions, common in lupus nephritis (LN), are associated with long-term
poor outcomes. There are mainly five pathological types of renal microvascular lesions in …

Ocular microvascular damage in autoimmune rheumatic diseases: The pathophysiological role of the immune system

E Hysa, CA Cutolo, E Gotelli, S Paolino… - Autoimmunity …, 2021 - Elsevier
Pathological eye involvement represents a quite common finding in a broad spectrum of
autoimmune rheumatic diseases (ARDs). Ocular signs, often occur as early manifestations …

Lupus enteritis: clinical characteristics, risk factor for relapse and association with anti-endothelial cell antibody

SK Kwok, SH Seo, JH Ju, KS Park, CH Yoon… - Lupus, 2007 - journals.sagepub.com
The study was undertaken to evaluate clinical and laboratory characteristics of patients with
lupus enteritis and to investigate its association with anti-endothelial cell antibodies …