Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Ferroptosis is the type of cell death arising from uncontrolled and excessive lipid
peroxidation. NADPH is essential for ferroptosis regulation because it supplies reducing …

The process of dead cell clearance by phagocytic cells, called efferocytosis, prevents
inflammatory cell necrosis and promotes resolution and repair. Defective efferocytosis …

Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …

Ferroptosis is an oxidative damage-related, iron-dependent regulated cell death with
intracellular lipid peroxide accumulation, which is associated with many physiological and …

Ferroptosis, an iron-dependent form of regulated cell death, results in lipid peroxidation of
polyunsaturated fatty acids in the cell membrane, which is catalyzed by iron ions and …

Abstract Transmembrane protein 16A (TMEM16A) is one of the members of the ten-member
family of “transmembrane protein 16”, playing critical roles in infection and solid organ injury …

Ferroptosis has attracted attention throughout the last decade because of its tremendous
clinical importance. Here, we review the rapidly growing body of literature on how inhibition …

Abstract GPX4 (Glutathione peroxidase 4) serves as a crucial intracellular regulatory factor,
participating in various physiological processes and playing a significant role in maintaining …

Older livers are more prone to hepatic ischaemia/reperfusion injury (HIRI), which severely
limits their utilization in liver transplantation. The potential mechanism remains unclear …