Retrograde transport from endosomes to the trans-Golgi network is essential for recycling of
protein and lipid cargoes to counterbalance anterograde membrane traffic. Protein cargo …

The Golgi complex is the membrane-bound organelle that lies at the center of the secretory
pathway. Its main functions are to maintain cellular lipid homeostasis, to orchestrate protein …

Membrane trafficking contributes to distinct protein compositions of organelles and is
essential for proper organellar maintenance and functions. The trans-Golgi network (TGN) …

Cellular membranes serve as an epicentre combining extracellular and cytosolic
components with membranous effectors, which together support numerous fundamental …

Profilins (PFNs) are key regulatory proteins for the actin polymerization in cells and are
encoded in mouse and humans by four Pfn genes. PFNs are involved in cell mobility, cell …

Biological super-resolution microscopy is a new generation of imaging techniques that
overcome the~ 200 nm diffraction limit of conventional light microscopy in spatial resolution …

The trafficking of proteins such as aquaporin-2 (AQP2) in the exocytotic pathway requires an
active actin cytoskeleton network, but the mechanism is incompletely understood. Here, we …

Determination of the intracellular location of proteins is one of the fundamental tasks of
microbiology. Conventionally, label-based microscopy and super-resolution techniques are …

Planar cell polarity (PCP) is a process during which cells are polarized along the plane of
the epithelium and is regulated by several transmembrane signaling proteins. After their …

The subcellular localization of Arf family proteins is generally thought to be determined by
their corresponding guanine nucleotide exchange factors. By promoting GTP binding …