Antimicrobial peptides: An alternative to traditional antibiotics

S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2023 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …

Antimicrobial peptides

NSMH Mohaideen, S Vaani, S Hemalatha - Current Pharmacology …, 2023 - Springer
Abstract Purpose of Review The review provides deep understanding on antimicrobial
peptides, properties, mechanisms, role in treating diseases, computational drug design, and …

Designing antimicrobial peptides using deep learning and molecular dynamic simulations

Q Cao, C Ge, X Wang, PJ Harvey… - Briefings in …, 2023 - academic.oup.com
With the emergence of multidrug-resistant bacteria, antimicrobial peptides (AMPs) offer
promising options for replacing traditional antibiotics to treat bacterial infections, but …

Bioactive Molecules from the Innate Immunity of Ascidians and Innovative Methods of Drug Discovery: A Computational Approach Based on Artificial Intelligence

L La Paglia, M Vazzana, M Mauro, A Urso, V Arizza… - Marine Drugs, 2023 - mdpi.com
The study of bioactive molecules of marine origin has created an important bridge between
biological knowledge and its applications in biotechnology and biomedicine. Current studies …

A novel stacking-based predictor for accurate prediction of antimicrobial peptides

S Kanwal, R Arif, S Ahmed, M Kabir - Journal of Biomolecular …, 2024 - Taylor & Francis
Antimicrobial peptides (AMPs) are gaining acceptance and support as a chief antibiotic
substitute since they boost human immunity. They retain a wide range of actions and have a …

Diff-AMP: tailored designed antimicrobial peptide framework with all-in-one generation, identification, prediction and optimization

R Wang, T Wang, L Zhuo, J Wei, X Fu… - Briefings in …, 2024 - academic.oup.com
Antimicrobial peptides (AMPs), short peptides with diverse functions, effectively target and
combat various organisms. The widespread misuse of chemical antibiotics has led to …

In SilicoDesign and Synthesis of Antifungal Peptides Guided by Quantitative Antifungal Activity

J Zhang, X Sun, H Zhao, X Zhou, Y Zhang… - Journal of Chemical …, 2024 - ACS Publications
Antifungal peptides (AFPs) are emerging as promising candidates for advanced antifungal
therapies because of their broad-spectrum efficacy and reduced resistance development. In …

[PDF][PDF] Computational biology in topical bioactive peptide discovery for cosmeceutical application: a concise review

XH Li, WR Su, FF Wang - Biomed Eng Commun, 2023 - tmrjournals.com
Regenerative medicine and anti-aging research have made great strides at the molecular
and cellular levels in dermatology and the medical aesthetic field, targeting potential …

人工智能方法在抗菌肽筛选领域的应用及展望

薛凤, 封硕, 李菁 - 中国药科大学学报, 2023 - jcpu.cpu.edu.cn
抗菌肽(antimicrobial peptides, AMPs) 是一类具有广谱抗菌活性的小分子肽,
其独特抗菌机制能够有效治疗感染性疾病, 且不易产生耐药性. 然而, 利用传统实验方式虽然能够 …

MP-MIENN: predicting multifunctional peptides by neural network with multiangle initialization embedding

J Xu, X Ruan, J Yang, S Xia, S Li - 2023 9th International …, 2023 - ieeexplore.ieee.org
Functional peptide has been utilized widely in the treatment of disease due to its high
absorption rate, low toxicity, and biological activity, making it a possible substitute for …