Imaging in acute respiratory distress syndrome

A Pesenti, G Musch, D Lichtenstein, F Mojoli… - Intensive care …, 2016 - Springer
Purpose Imaging has become increasingly important across medical specialties for
diagnostic, monitoring, and investigative purposes in acute respiratory distress syndrome …

Close down the lungs and keep them resting to minimize ventilator-induced lung injury

P Pelosi, PRM Rocco, M Gama de Abreu - Critical Care, 2018 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2018. Other selected articles can be found online at https://www …

Comparative effects of volutrauma and atelectrauma on lung inflammation in experimental acute respiratory distress syndrome

A Güldner, A Braune, L Ball, PL Silva… - Critical care …, 2016 - journals.lww.com
Objective: Volutrauma and atelectrauma promote ventilator-induced lung injury, but their
relative contribution to inflammation in ventilator-induced lung injury is not well established …

Effect of local tidal lung strain on inflammation in normal and lipopolysaccharide-exposed sheep

TJ Wellman, T Winkler, ELV Costa, G Musch… - Critical care …, 2014 - journals.lww.com
Objectives: Regional tidal lung strain may trigger local inflammation during mechanical
ventilation, particularly when additional inflammatory stimuli are present. However, it is …

The association of postoperative pulmonary complications in 109,360 patients with pressure‐controlled or volume‐controlled ventilation

A Bagchi, MI Rudolph, PY Ng, FP Timm, DR Long… - …, 2017 - Wiley Online Library
We thought that the rate of postoperative pulmonary complications might be higher after
pressure‐controlled ventilation than after volume‐controlled ventilation. We analysed peri …

Regional tidal lung strain in mechanically ventilated normal lungs

LF Paula, TJ Wellman, T Winkler… - Journal of Applied …, 2016 - journals.physiology.org
Parenchymal strain is a key determinant of lung injury produced by mechanical ventilation.
However, imaging estimates of volumetric tidal strain (ε= regional tidal volume/reference …

Effects of positive end-expiratory pressure and spontaneous breathing activity on regional lung inflammation in experimental acute respiratory distress syndrome

T Kiss, T Bluth, A Braune, R Huhle, A Denz… - Critical care …, 2019 - journals.lww.com
Objectives: To determine the impact of positive end-expiratory pressure during mechanical
ventilation with and without spontaneous breathing activity on regional lung inflammation in …

Temporal trends and current practice patterns for intraoperative ventilation at US academic medical centers: a retrospective study

JP Wanderer, JM Ehrenfeld, RH Epstein, DJ Kor… - BMC …, 2015 - Springer
Background Lung protective ventilation strategies utilizing lower tidal volumes per predicted
body weight (PBW) and positive end-expiratory pressure (PEEP) have been suggested to be …

Ventilation heterogeneity in asthma

WG Teague, NJ Tustison, TA Altes - Journal of Asthma, 2014 - Taylor & Francis
Non-uniform distribution of inspired gas within the lung, termed ventilation heterogeneity, is
present in patients with even mild asthma. Current evidence strongly supports ventilation …

Proteomics of lung tissue reveals differences in inflammation and alveolar-capillary barrier response between atelectasis and aerated regions

A Rashid, C Zeng, G Motta-Ribeiro, ST Dillon… - Scientific Reports, 2022 - nature.com
Atelectasis is a frequent clinical condition, yet knowledge is limited and controversial on its
biological contribution towards lung injury. We assessed the regional proteomics of …