[HTML][HTML] Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Mechanisms of lncRNA/microRNA interactions in angiogenesis

Z Zhao, W Sun, Z Guo, J Zhang, H Yu, B Liu - Life sciences, 2020 - Elsevier
Angiogenesis is a complex physiological process. However, over the past couple of
decades, abnormally accelerated or pathological angiogenesis has garnered greater …

RNA-based diagnostic markers discovery and therapeutic targets development in cancer

H Wang, Q Meng, J Qian, M Li, C Gu, Y Yang - Pharmacology & …, 2022 - Elsevier
The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …

The complex role of MEG3: An emerging long non-coding RNA in breast cancer

MS Hussain, AA Majami, H Ali, G Kumar… - … -Research and Practice, 2023 - Elsevier
MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …

[HTML][HTML] Long non-coding RNAs in gastric cancer: New emerging biological functions and therapeutic implications

H Tan, S Zhang, J Zhang, L Zhu, Y Chen, H Yang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Gastric cancer (GC) is currently the fourth most common malignancy and the third leading
cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) …

[HTML][HTML] The emerging role of the long non-coding RNA HOTAIR in breast cancer development and treatment

H Mozdarani, V Ezzatizadeh… - Journal of translational …, 2020 - Springer
Despite considering vast majority of the transcribed molecules as merely noise RNA in the
last decades, recent advances in the field of molecular biology revealed the mysterious role …

[HTML][HTML] Exosomal long non-coding RNAs in lung diseases

C Poulet, MS Njock, C Moermans, E Louis… - International journal of …, 2020 - mdpi.com
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …

[HTML][HTML] Long noncoding RNA Meg3 sponges miR-708 to inhibit intestinal tumorigenesis via SOCS3-repressed cancer stem cells growth

S Zhang, WW Ji, W Wei, LX Zhan, X Huang - Cell Death & Disease, 2021 - nature.com
Background Colorectal cancer (CRC) remains the most common gastrointestinal cancer and
a leading cause of cancer deaths worldwide, with most showing pathologies indicating the …

Molecular landscape of long noncoding RNAs in brain disorders

S Yang, KH Lim, SH Kim, JY Joo - Molecular psychiatry, 2021 - nature.com
According to current paradigms, various risk factors, such as genetic mutations, oxidative
stress, neural network dysfunction, and abnormal protein degradation, contribute to the …

[HTML][HTML] Unraveling immune-related lncRNAs in breast cancer molecular subtypes

C Mathias, JCD Muzzi, BB Antunes, DF Gradia… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BRCA) is the most leading cause of cancer worldwide. It is a heterogeneous
disease with at least five molecular subtypes including luminal A, luminal B, basal-like …