Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Intermittent fasting diets have become very popular in the past few years, as they can
produce clinically significant weight loss. These diets can be defined, in the simplest of …

Mitochondria are the main source of reactive oxygen species (ROS) in cells. Early studies
have shown that mitochondrial reactive oxygen species (mROS) are related to the …

Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …

Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

Time-restricted feeding (TRF) regimens have grown in popularity; however, very few studies
have examined their weight-loss efficacy. We conducted the first human trial (Clinicaltrials …

This review addresses the role of the essential trace element, selenium, in type-2 diabetes
mellitus (T2DM) and its metabolic co-morbidities, ie, metabolic syndrome, obesity and non …

This review aims to summarize the effects of intermittent fasting on markers of
cardiometabolic health in humans. All forms of fasting reviewed here—alternate-day fasting …

Globally, the incidence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD)
epidemics is increasing rapidly and has huge financial and emotional costs. The purpose of …

Most human cells utilize glucose as the primary substrate, cellular uptake requiring insulin.
Insulin signaling is therefore critical for these tissues. However, decrease in insulin …