Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders worldwide. There are currently no cures or preventative treatments for PD …

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …

Parkinson's disease is a common progressive neurodegenerative disease, and presently
has no curative agent. Curcumin, as one of the natural polyphenols, has great potential in …

Background Alzheimer's disease (AD) is an insidious, irreversible, and progressive
neurodegenerative health condition manifesting as cognitive deficits and amyloid beta (Aβ) …

Genetic disorders and congenital abnormalities are present in 2-5% of births all over the
world and can cause up to 50% of all early childhood deaths. The establishment of …

The etiology of many neurological diseases affecting the central nervous system (CNS) is
unknown and still needs more effective and specific therapeutic approaches. Gene therapy …

Alzheimer's disease (AD) is a progressive degenerative neurological illness with insidious
onset. Due to the complexity of the pathogenesis of AD and different pathological changes …

Choroid plexus (ChP) epithelial cells are crucial for the function of the blood-cerebrospinal
fluid barrier (BCSFB) in the developing and mature brain. The ChP is considered the primary …

The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …

Many adult and most childhood neurological diseases have a genetic basis. CRISPR/Cas9
biotechnology holds great promise in neurological therapy, pending the clearance of major …