[HTML][HTML] Alzheimer's disease: an updated overview of its genetics
J Andrade-Guerrero, A Santiago-Balmaseda… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …
classified as familial and sporadic. The dominant familial or autosomal presentation …
[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
[HTML][HTML] Clinical applications of stem cell-derived exosomes
F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …
certain diseases more successfully than conventional surgery, it nevertheless comes with …
[HTML][HTML] Incretin and insulin signaling as novel therapeutic targets for Alzheimer's and Parkinson's disease
J Nowell, E Blunt, P Edison - Molecular Psychiatry, 2023 - nature.com
Despite an ever-growing prevalence and increasing economic burden of Alzheimer's
disease (AD) and Parkinson's disease (PD), recent advances in drug development have …
disease (AD) and Parkinson's disease (PD), recent advances in drug development have …
[HTML][HTML] Citrus waste as source of bioactive compounds: Extraction and utilization in health and food industry
The current research was conducted to extract the bioactive compounds from citrus waste
and assess their role in the development of functional foods to treat different disorders. The …
and assess their role in the development of functional foods to treat different disorders. The …
[HTML][HTML] Machine learning for dementia prediction: a systematic review and future research directions
Abstract Nowadays, Artificial Intelligence (AI) and machine learning (ML) have successfully
provided automated solutions to numerous real-world problems. Healthcare is one of the …
provided automated solutions to numerous real-world problems. Healthcare is one of the …
Role of Nrf2 in aging, Alzheimer's and other neurodegenerative diseases
M George, M Tharakan, J Culberson, AP Reddy… - Ageing Research …, 2022 - Elsevier
Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …
[HTML][HTML] Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age
A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …
diseases. The exact etiology of these disorders is not well known; however, environmental …
Reimagining cholinergic therapy for Alzheimer's disease
E Giacobini, AC Cuello, A Fisher - Brain, 2022 - academic.oup.com
Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …
represents the main available approach to treat cognitive and behavioural symptoms of the …