[HTML][HTML] Alzheimer's disease: an updated overview of its genetics

J Andrade-Guerrero, A Santiago-Balmaseda… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …

[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

[HTML][HTML] Clinical applications of stem cell-derived exosomes

F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

[HTML][HTML] Incretin and insulin signaling as novel therapeutic targets for Alzheimer's and Parkinson's disease

J Nowell, E Blunt, P Edison - Molecular Psychiatry, 2023 - nature.com
Despite an ever-growing prevalence and increasing economic burden of Alzheimer's
disease (AD) and Parkinson's disease (PD), recent advances in drug development have …

[HTML][HTML] Citrus waste as source of bioactive compounds: Extraction and utilization in health and food industry

Z Maqbool, W Khalid, HT Atiq, H Koraqi, Z Javaid… - Molecules, 2023 - mdpi.com
The current research was conducted to extract the bioactive compounds from citrus waste
and assess their role in the development of functional foods to treat different disorders. The …

[HTML][HTML] Machine learning for dementia prediction: a systematic review and future research directions

A Javeed, AL Dallora, JS Berglund, A Ali, L Ali… - Journal of medical …, 2023 - Springer
Abstract Nowadays, Artificial Intelligence (AI) and machine learning (ML) have successfully
provided automated solutions to numerous real-world problems. Healthcare is one of the …

Role of Nrf2 in aging, Alzheimer's and other neurodegenerative diseases

M George, M Tharakan, J Culberson, AP Reddy… - Ageing Research …, 2022 - Elsevier
Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …

[HTML][HTML] Alzheimer disease

A Kumar, J Sidhu, A Goyal, JW Tsao - 2018 - europepmc.org
Objectives: Identify the risk factors associated with Alzheimer disease. Describe the atypical
presentations of Alzheimer disease. Summarize and differentiate between the preclinical …

[HTML][HTML] Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

Reimagining cholinergic therapy for Alzheimer's disease

E Giacobini, AC Cuello, A Fisher - Brain, 2022 - academic.oup.com
Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …