[HTML][HTML] The initiation of oxidative stress and therapeutic strategies in wound healing

G Wang, F Yang, W Zhou, N Xiao, M Luo… - Biomedicine & …, 2023 - Elsevier
When the production of reactive oxygen species (ROS) is overloaded surpassing the
capacity of the reductive rheostat, mammalian cells undergo a series of oxidative damage …

Preclinical study of diabetic foot ulcers: From pathogenesis to vivo/vitro models and clinical therapeutic transformation

Y Du, J Wang, W Fan, R Huang… - International Wound …, 2023 - Wiley Online Library
Diabetic foot ulcer (DFU), a common intractable chronic complication of diabetes mellitus
(DM), has a prevalence of up to 25%, with more than 17% of the affected patients at risk of …

Hydrogel with ROS scavenging effect encapsulates BR@ Zn-BTB nanoparticles for accelerating diabetic mice wound healing via multimodal therapy

JJ Hu, XZ Yu, SQ Zhang, YX Zhang, XL Chen, ZJ Long… - Iscience, 2023 - cell.com
The strategies for eliminating excess reactive oxygen species (ROS) or suppressing
inflammatory responses on the wound bed have proven effective for diabetic wound healing …

Immunostimulatory activity and structure-activity relationship of epimedin B from Epimedium brevicornu Maxim.

Y Gao, W Shi, C Tu, P Li, G Zhao, X Xiao… - Frontiers in …, 2022 - frontiersin.org
Epimedii Folium (EF, Epimedium brevicornu Maxim.), a traditional botanical drug, is famous
for treating bone fractures, joint diseases, and several chronic illnesses. However, some …

Transcriptional profiling and circRNA-miRNA-mRNA network analysis identify the biomarkers in Sheng-ji Hua-yu formula treated diabetic wound healing

Y Xiang, L Kuai, Y Ru, J Jiang, X Li, F Li… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Sheng-ji Hua-yu (SJHY) formula is a traditional
Chinese herbal which is effective in treating diabetic ulcers. It has been indicated to …

Intragastric administration of Pien Tze Huang enhanced wound healing in diabetes by inhibiting inflammation and improving energy generation

J Zhang, G Cao, L Tian, J Hou, Y Zhang, H Xu, M Wang… - Phytomedicine, 2023 - Elsevier
Background and purpose As a complex and challenging complication for the patients with
diabetes mellitus, diabetic ulcers are difficult to heal and current strategies cannot fulfill the …

[HTML][HTML] Dual effects of bisphenol A on wound healing, involvement of estrogen receptor β

X Wen, M Zhu, Z Li, T Li, X Xu - Ecotoxicology and Environmental Safety, 2022 - Elsevier
Bisphenol A (BPA) is a ubiquitous environmental pollutant that can specifically induce
estrogen receptor β (ERβ) expression, and the latter plays a crucial role during wound …

The role of programmed cell death in diabetic foot ulcers

J Li, C Jiang, J Xia - International Wound Journal, 2024 - Wiley Online Library
Diabetic foot ulcer, is a chronic complication afflicting individuals with diabetes, continue to
increase worldwide, immensely burdening society. Programmed cell death, which includes …

Precise design of alginate hydrogels crosslinked with microgels for diabetic wound healing

Y Yan, P Ren, Q Wu, T Zhang - Biomolecules, 2022 - mdpi.com
Alginate hydrogel has received great attention in diabetic wound healing. However, the
limited tunability of the ionic crosslinking method prevents the delicate management of …

Novel therapeutic targets for diabetes-related wounds or ulcers: an update on preclinical and clinical research

J Golledge, S Thanigaimani - Expert Opinion on Therapeutic …, 2021 - Taylor & Francis
Introduction Diabetes-related wounds, particularly diabetes-related foot ulcers, are mainly
caused by lack of foot sensation and high plantar tissue stress secondary to peripheral …