Implication of gut microbiota in cardiovascular diseases

W Zhou, Y Cheng, P Zhu, MI Nasser… - Oxidative medicine …, 2020 - Wiley Online Library
Emerging evidence has identified the association between gut microbiota and various
diseases, including cardiovascular diseases (CVDs). Altered intestinal flora composition has …

Inflammasome Signaling in Atrial Fibrillation: JACC State-of-the-Art Review

A Ajoolabady, S Nattel, GYH Lip, J Ren - Journal of the American College …, 2022 - jacc.org
As the most prevalent form of arrhythmia, atrial fibrillation (AF) increases the risk of heart
failure, thromboembolism, and stroke, contributing to the raising mortality and morbidity in …

[HTML][HTML] Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling

K Zuo, C Fang, Z Liu, Y Fu, Y Liu, L Liu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Rationale: Dysbiotic gut microbiota (GM) and NLRP3 inflammasome are proarrhythmic
factors in atrial fibrillation (AF). Herein, whether short-chain fatty acid (SCFA) produced from …

Gut microbiome and atrial fibrillation—results from a large population-based study

J Palmu, CS Börschel, A Ortega-Alonso, L Markó… - …, 2023 - thelancet.com
Background Atrial fibrillation (AF) is an important heart rhythm disorder in aging populations.
The gut microbiome composition has been previously related to cardiovascular disease risk …

Dysbiosis is one of the risk factor for stroke and cognitive impairment and potential target for treatment

M Koszewicz, J Jaroch, A Brzecka, M Ejma… - Pharmacological …, 2021 - Elsevier
More than 50 million people have various forms of cognitive impairment basically caused by
neurodegenerative diseases, such as Alzheimer's, Parkinson's, and cerebrovascular …

Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications

M Gawałko, TA Agbaedeng, A Saljic… - Cardiovascular …, 2022 - academic.oup.com
Recent preclinical and observational cohort studies have implicated imbalances in gut
microbiota composition as a contributor to atrial fibrillation (AF). The gut microbiota is a …

Gut microbiota dysbiosis induced by a high-fat diet increases susceptibility to atrial fibrillation

B Kong, H Fu, Z Xiao, Y Zhou, W Shuai… - Canadian Journal of …, 2022 - Elsevier
Background Obesity is a significant risk factor for atrial fibrillation (AF), and the gut
microbiota is closely related to obesity-induced diseases. However, whether the gut …

The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives

N Li, L Wang, L Li, MZ Yang, QX Wang, XW Bai… - Military Medical …, 2023 - Springer
Regulation of gut microbiota and its impact on human health is the theme of intensive
research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating …

Gut microbiota dysbiosis in acute ischemic stroke associated with 3-month unfavorable outcome

H Sun, M Gu, Z Li, X Chen, J Zhou - Frontiers in Neurology, 2022 - frontiersin.org
Background Alterations in the gut microbiota after ischemic stroke have been demonstrated,
whereas the effect on stroke outcome remains to be established. Methods A total of 132 …

The emerging role of the gut microbiome in cardiovascular disease: Current knowledge and perspectives

PD Papadopoulos, C Tsigalou, PN Valsamaki… - Biomedicines, 2022 - mdpi.com
The collection of normally non-pathogenic microorganisms that mainly inhabit our gut lumen
shapes our health in many ways. Structural and functional perturbations in the gut microbial …