Biochemical and cellular basis of oxidative stress: implications for disease onset

K Aramouni, R Assaf, A Shaito… - Journal of Cellular …, 2023 - Wiley Online Library
Cellular oxidation–reduction (redox) systems, which encompass pro‐and antioxidant
molecules, are integral components of a plethora of essential cellular processes. Any …

A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

I Tahir, KA Alkheraije - Frontiers in Veterinary Science, 2023 - frontiersin.org
Toxicity with heavy metals has proven to be a significant hazard with several health
problems linked to it. Heavy metals bioaccumulate in living organisms, pollute the food …

Nature-inspired allomelanin nanomedicine alleviates cardiac ischemia/reperfusion injury via scavenging free radicals and ameliorating myocardial microenvironment

X Mo, H Xiang, L Wei, L Xia, X Chen, Y Chen, B Zhang - Nano Today, 2022 - Elsevier
Myocardial ischemia/reperfusion (I/R) injury is the resultantly pathological heart damage
from the restoration of blood supply through percutaneous coronary intervention. Herein …

Bioactive components and molecular mechanisms of Salvia miltiorrhiza Bunge in promoting blood circulation to remove blood stasis

B Wei, C Sun, H Wan, Q Shou, B Han, M Sheng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge (SM) is an outstanding
herbal medicine with various traditional effects, especially promoting blood circulation to …

Portrayal of NLRP3 inflammasome in atherosclerosis: current knowledge and therapeutic targets

DM Tanase, E Valasciuc, EM Gosav, A Ouatu… - International Journal of …, 2023 - mdpi.com
We are witnessing the globalization of a specific type of arteriosclerosis with rising
prevalence, incidence and an overall cardiovascular disease burden. Currently …

Vascular inflammatory diseases and endothelial phenotypes

J Immanuel, S Yun - Cells, 2023 - mdpi.com
The physiological functions of endothelial cells control vascular tone, permeability,
inflammation, and angiogenesis, which significantly help to maintain a healthy vascular …

Oxidative stress and microRNAs in endothelial cells under metabolic disorders

M Minjares, W Wu, JM Wang - Cells, 2023 - mdpi.com
Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …

Research Progress of Flavonoids Regulating Endothelial Function

H Li, Q Zhang - Pharmaceuticals, 2023 - mdpi.com
The endothelium, as the guardian of vascular homeostasis, is closely related to the
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …

Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism

G Scarfò, S Daniele, E Chelucci, A Rizza, J Fusi… - Scientific Reports, 2023 - nature.com
Aging is the basis for several unfavorable conditions, including cardiovascular diseases
(CVDs). In this sense, regular physical activity (regular PA) has been proven to delay cellular …

Paradoxical effects of statins on endothelial and cancer cells: The impact of concentrations

Y Ahmadi, JK Fard, D Ghafoor, AH Eid… - Cancer Cell …, 2023 - Springer
In addition to their lipid-lowering functions, statins elicit additional pleiotropic effects on
apoptosis, angiogenesis, inflammation, senescence, and oxidative stress. Many of these …