The pathophysiology of reperfusion injury is a complex process that causes cardiomyocyte
death via multiple mechanisms and involves the alteration and interplay of a variety of …

Cardiomyocyte loss is the main cause of myocardial dysfunction following an ischemia-
reperfusion (IR) injury. Mitochondrial dysfunction and altered mitochondrial network …

Although heart disease is the primary cause of death in several industrialized nations, there
are no widely-used therapies targeting the ischemic heart muscle; current therapies focus on …

Los resultados del presente trabajo de Tesis, muestran que en el corazón atontado se
desencadena el estrés de RE, con estimulación de las 3 vías de la UPR y activación de …

Glia form a central component of the nervous system whose varied activities sustain an
environment that is optimised for healthy development and neuronal function. Alpha-amino …

Halogens are widely used, highly toxic chemicals that pose a potential threat to humans
because of their abundance. Halogens such as bromine (Br2) cause severe pulmonary and …

Chronic hypoxia exacerbates proliferation of pulmonary arterial smooth muscle cells
(PASMC), thereby reducing the lumen of pulmonary arteries. This leads to poor blood …

Maintaining the equilibrium between saturated and unsaturated fatty acids within membrane
phospholipids (PLs) is crucial to sustain the optimal membrane biophysical properties …

Lung cancer is considered as one of the most important causes of cancer-related death
worldwide and Non-Small Cell Lung Cancer (NSCLC) accounts for 80% of all lung cancer …

Human cardiac ryanodine receptors (hRyR2) are calcium (Ca2+) release channels central
to excitation-contraction coupling. Mutations in hRyR2 are linked to catecholaminergic …