Synthesis, characterization, biological potency, and molecular docking of Co2+, Ni2+ and Cu2+ complexes of a benzoyl isothiocyanate based ligand

ES Al-Farraj, AM Younis, GMIA El-Reash - Scientific Reports, 2024 - nature.com
The primary objective of the present study was to produce metal complexes of H4DAP
ligand (N, N'-((pyridine-2, 6-diylbis (azanediyl)) bis (carbonothioyl)) dibenzamide) derived …

Dendritic Pyridine–Imine Copper Complexes as Metallo-Drugs

R Laurent, V Maraval, V Bernardes-Génisson… - Molecules, 2024 - mdpi.com
Since the discovery of cisplatin in the 1960s, the search for metallo-drugs that are more
efficient than platinum complexes with negligible side effects has attracted much interest …

Co-targeting CDK 4/6 and C-MYC/STAT3/CCND1 axis and inhibition of tumorigenesis and epithelial-mesenchymal-transition in triple negative breast cancer by Pt (II) …

Z Lv, A Ali, N Wang, H Ren, L Liu, F Yan, M Shad… - Journal of Inorganic …, 2024 - Elsevier
In search of potential anticancer agents, we synthesized SNO-donor salicylaldimine main
ligand-based Pt (II) complexes bearing NH 3 as co-ligand at trans-position (C1-C6). These …

Zinc (II) coordination compound with N′-(pyridin-2-ylmethylene) nicotinohydrazide: Synthesis, crystal structure, computational and cytotoxicity studies

S Adhikari, S Nath, S Kansız, N Balidya, AK Paul… - Journal of Inorganic …, 2024 - Elsevier
In this work, we report on the synthesis of a novel zinc (II) coordination compound [ZnL 2](1),
which was readily obtained from the reaction of Zn (OAc)· 2H 2 O and N′-(pyridin-2 …

[HTML][HTML] Ruthenium p-Cymene Complexes Incorporating Substituted Pyridine–Quinoline-Based Ligands: Synthesis, Characterization, and Cytotoxic Properties

A Kokkosi, E Garofallidou, N Zacharopoulos… - Molecules, 2024 - mdpi.com
Organometallic complexes of the formula [Ru (N^ N)(p-cymene) Cl][X](N^ N= bidentate
polypyridyl ligands, p-cymene= 1-methyl-4-(1-methylethyl)-benzene, X= counter anion), are …

[PDF][PDF] Metal-Based Drugs in Cancer Therapy

S Nath, A Datta, A Das, S Adhikari - Int. J. Exp. Res. Rev, 2024 - researchgate.net
Metal-based drugs have emerged as pivotal therapeutics in cancer therapy, enlightening a
path toward innovative and effective treatment strategies. Platinum-based therapeutics …

Supramolecular assemblies of Zn (II) complex based on dithiolate-amine binary ligands: Synthesis, crystal structure, Hirshfeld surface, DFT, molecular docking, and …

T Bhattacharjee, S Nath, N Baildya, A Das… - Inorganic Chemistry …, 2024 - Elsevier
In this article, synthesis of the novel zinc (II) complex [Zn (tren)(i-mnt)] from
diethylenetriamine (tren) and 1, 1-dicyano-2, 2-ethylenedithiolate di-potassium salt (K 2 i …

Platinum (II) complexes bearing the simplest olefin ligand: A new class potential for the development of anticancer drugs

NTB Linh, NH Ninh, P Van Thong, TN Dung… - Polyhedron, 2024 - Elsevier
Six new Pt (II) complexes containing ethylene and amine including trans-[PtCl 2 (C 2 H
4)(N)](N: caffeine/1; PyCOOH/2, PyCONH 2/3; i PrOQ/4) and [PtCl (C 2 H 4)](N^ O)](N^ O …

[HTML][HTML] Synthesis and characterisation of dipyrromethene Cu (II) complexes: A preliminary DNA intercalation study

N Sarang, ML Bracken, M Nowakowska, S Mathura - Polyhedron, 2024 - Elsevier
Copper complexes of the bilirubin bile pigment have been shown to affect DNA. It was
suggested that the copper ions within these metal-bilirubin therapeutics bind to bilirubin …