Consequences of presynaptic dysfunction in Alzheimer's Disease models

H Taylor - 2020 - ora.ox.ac.uk
Soluble oligomeric assemblies of amyloid β (Aβo) drive much of Alzheimer's disease (AD)
pathology. Among these, changes in synaptic plasticity including attenuated long-term …

[PDF][PDF] Dendritic spines are lost in clusters in patients with Alzheimer's disease

M Mijalkov, G Volpe, I Fernaud-Espinosa, J DeFelipe… - scholar.archive.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a
deterioration of neuronal connectivity. The pathological accumulation of tau protein in …

[PDF][PDF] BRAIN COMMUNICATIONS AIN COMMUNICATIONS

V Corsetti, A Borreca, V Latina, G Giacovazzo… - iris.cnr.it
Abbreviations: Ab ¼ amyloid-b peptides; APP ¼ amyloid precursor protein; DO ¼ displaced
object; EE ¼ energy expenditure; ELISA ¼ enzyme-linked immunosorbent assay; FO ¼ …

The Neuropeptide Kyotorphin as a Possible Biomarker and Neuroprotective Agent in Alzheimer's Disease

HT Angelova, DM Pechlivanova, BV Landzhov… - Journal of Biomedical … - sciendo.com
Alzheimer's disease (AD) is an age-related neurodegenerative disorder clinically
characterized by memory impairment, disorientation, cognitive deficits, and behavioral …

Le chat âgé comme modèle translationnel de maladies neurodégénératives chez l'homme, approches histologique et par IRM

M Escudier-Donnadieu, A Limozin - 2021 - oatao.univ-toulouse.fr
Avec une population de plus en plus vieillissante, l'incidence de maladies
neurodégénératives telle que la maladie d'Alzheimer a augmenté. Grâce au progrès de la …

Understanding Prion-like Mechanisms of Tauopathy in Traumatic Brain Injury Using Novel in vivo Models

HE Alyenbaawi - 2020 - era.library.ualberta.ca
Traumatic brain injury (TBI) is broadly acknowledged as a source of mortality and disability
worldwide. It is one of the key risk factors resulting in neurodegeneration and the …

[PDF][PDF] Palmitoylation in Alzheimer's disease and other

EC Park - Mol Cell Biol, 2007 - cyberleninka.org
Posttranslational modifications of proteins are important regulatory processes endowing the
proteins functional complexity. Over the last decade, numerous studies have shed light on …

Stratégie de prévention de la maladie d'Alzheimer: Étude du rôle de la vitamine A

EF Biyong - 2019 - theses.hal.science
La vitamine A (VA), ou rétinol, est une molécule essentielle au maintien des processus
neurobiologiques de la mémoire tout au long de la vie. Dans le cerveau, le rétinol est …

The Role of Tau Protein in the Stress-Induced Changes in Adult Hippocampal Neurogenesis

C Dioli - 2016 - search.proquest.com
A exposição ao stress cronico aumenta a susceptibilidade para patologias ligadas ao
cérebro e esta associada com alterações de neuroplasticidade e défices cognitivos. O …

[PDF][PDF] Modulating copper metabolism as a strategy to treat neurodegenerative tauopathies

S McKenzie-Nickson - 2017 - minerva-access.unimelb.edu.au
Transition metals such as iron and copper are essential for life and health and yet can cause
toxicity through oxidative damage. Therefore, regulation of the levels and location of …