Acute pancreatitis may be associated with both local and systemic complications. Systemic
injury manifests in the form of organ failure, which is seen in approximately 20% of all cases …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in
relation to the development of chronic diseases have been somewhat demonised. However …

1.1. Discovery of the Phospholipase A2 Superfamily Phospholipases represent one of the
earliest enzyme activities to be identified and studied, and the phospholipase A2 (PLA2) …

The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …

Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …

A growing body of evidence indicates that resolution of acute inflammation is an active
process,. Resolvins are a new family of lipid mediators enzymatically generated within …

Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

The discovery of the colocalization of catalase with H2O2-generating oxidases in
peroxisomes was the first indication of their involvement in the metabolism of oxygen …

Mammalian genomes encode genes for more than 30 phospholipase A2s (PLA2s) or
related enzymes, which are subdivided into several classes including low-molecular-weight …