Toward low-cost biological and hybrid biological/catalytic conversion of cellulosic biomass to fuels
LR Lynd, GT Beckham, AM Guss… - Energy & …, 2022 - pubs.rsc.org
Developing economically viable, scalable, and sustainable technologies for the conversion
of lignocellulosic polysaccharides to liquid fuels is widely seen as a centerpiece of the …
of lignocellulosic polysaccharides to liquid fuels is widely seen as a centerpiece of the …
Common principles and best practices for engineering microbiomes
Despite broad scientific interest in harnessing the power of Earth's microbiomes, knowledge
gaps hinder their efficient use for addressing urgent societal and environmental challenges …
gaps hinder their efficient use for addressing urgent societal and environmental challenges …
Synthetic biology tools to engineer microbial communities for biotechnology
NS McCarty, R Ledesma-Amaro - Trends in biotechnology, 2019 - cell.com
Microbial consortia have been used in biotechnology processes, including fermentation,
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …
Metabolic engineering of Escherichia coli for natural product biosynthesis
Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …
Biotechnological basis of microbial consortia for the removal of pesticides from the environment
P Bhatt, K Bhatt, A Sharma, W Zhang… - Critical Reviews in …, 2021 - Taylor & Francis
The application of microbial strains as axenic cultures has frequently been employed in a
diverse range of sectors. In the natural environment, microbes exist as multispecies and …
diverse range of sectors. In the natural environment, microbes exist as multispecies and …
Escherichia coli as a host for metabolic engineering
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
Engineering microbial division of labor for plastic upcycling
T Bao, Y Qian, Y Xin, JJ Collins, T Lu - Nature communications, 2023 - nature.com
Plastic pollution is rapidly increasing worldwide, causing adverse impacts on the
environment, wildlife and human health. One tempting solution to this crisis is upcycling …
environment, wildlife and human health. One tempting solution to this crisis is upcycling …
Metabolic burden: cornerstones in synthetic biology and metabolic engineering applications
Engineering cell metabolism for bioproduction not only consumes building blocks and
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …
Biosynthesis of the highly oxygenated tetracyclic core skeleton of Taxol
C Yang, Y Wang, Z Su, L Xiong, P Wang, W Lei… - Nature …, 2024 - nature.com
Taxol is a widely-applied anticancer drug that inhibits microtubule dynamics in actively
replicating cells. Although a minimum 19-step biosynthetic pathway has been proposed and …
replicating cells. Although a minimum 19-step biosynthetic pathway has been proposed and …
Designing microbial consortia with defined social interactions
W Kong, DR Meldgin, JJ Collins, T Lu - Nature chemical biology, 2018 - nature.com
Designer microbial consortia are an emerging frontier in synthetic biology that enable
versatile microbiome engineering. However, the utilization of such consortia is hindered by …
versatile microbiome engineering. However, the utilization of such consortia is hindered by …