PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS
The plant homeodomain zinc-finger protein, PHF6, is a transcriptional regulator, and PHF6
germline mutations cause the X-linked intellectual disability (XLID) Börjeson-Forssman …
germline mutations cause the X-linked intellectual disability (XLID) Börjeson-Forssman …
Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
Background Transcription factors bind DNA in specific sequence contexts. In addition to
distinguishing one nucleobase from another, some transcription factors can distinguish …
distinguishing one nucleobase from another, some transcription factors can distinguish …
Uncovering methylation-dependent genetic effects on regulatory element function in diverse genomes
RM Petersen, CM Vockley, AJ Lea - bioRxiv, 2024 - biorxiv.org
A major goal in evolutionary biology and biomedicine is to understand the complex
interactions between genetic variants, the epigenome, and gene expression. However, the …
interactions between genetic variants, the epigenome, and gene expression. However, the …
Application of supervised learning models to compare epigenetic predictors of gene expression across healthy breast cell types
MA Tello Palencia - 2024 - open.library.ubc.ca
Moderate associations have been identified between gene expression and DNA methylation
variability, predicted transcription factor binding sites, and transcription factor expression …
variability, predicted transcription factor binding sites, and transcription factor expression …