Emotions depend upon the integrated activity of neural networks that modulate arousal,
autonomic function, motor control, and somatosensation. Brainstem nodes play critical roles …

The superior colliculus (SC), one of the most well-characterized midbrain sensorimotor
structures where visual, auditory, and somatosensory information are integrated to initiate …

BACKGROUND: Altered serotonergic function is thought to play a role in the
pathophysiology of major depressive episodes based upon evidence from neuroimaging …

In humans, affective consequences of neuropathic pain, ranging from depression to anxiety
and anhedonia, severely impair quality of life and are a major disease burden, often …

Background: Cannabis sativa-derived substances such as cannabidiol (CBD) have attracted
increasing clinical interest and consist in a new perspective for treating some neurological …

Background: A moral injury occurs when a deeply held moral code has been violated, and it
can lead to the development of symptoms of posttraumatic stress disorder (PTSD). However …

Several pharmacological targets have been proposed as modulators of panic-like reactions.
However, interest should be given to other potential therapeutic neurochemical agents …

The anterior cingulate cortex (ACC) Cg1 (24b) area modulates glutamate-mediated
unconditioned fear and antinociception organised by hypothalamus. However, it remains …

Epilepsy is associated with a variety of neuropsychiatric comorbidities, including both
anxiety and depression. Despite high occurrences of depression and anxiety seen in human …

Abstract Serotonin 5-hydroxytryptamine (5-HT) is a key neurotransmitter for the modulation
and/or regulation of numerous physiological processes and psychiatric disorders (eg …