Childhood Obesity, Hypothalamic Inflammation, and the Onset of Puberty: A Narrative Review

AM Tzounakou, G Stathori, G Paltoglou, G Valsamakis… - Nutrients, 2024 - mdpi.com
The onset of puberty, which is under the control of the hypothalamic–pituitary–gonadal
(HPG) axis, is influenced by various factors, including obesity, which has been associated …

Endocrine Disruptors and Metabolic Changes: Impact on Puberty Control

M Peralta, F Lizcano - Endocrine Practice, 2024 - Elsevier
Objective This study aims to explore the significant impact of environmental chemicals on
disease development, focusing on their role in developing metabolic and endocrine …

PACE: a novel eating behavior phenotype to assess risk for obesity in middle childhood

KL Keller, AL Pearce, B Fuchs, BJ Rolls, SJ Wilson… - The Journal of …, 2024 - Elsevier
Background Behavioral phenotypes that predict future weight gain are needed to identify
children susceptible to obesity. Objective This prospective study developed an eating …

Creatine Acts as a Mediator of the Causal Effect of Obesity on Puberty Onset in Girls: Evidence from Mediation Mendelian Randomization Study

C Jin, G Zhao - Metabolites, 2024 - mdpi.com
Epidemiological studies have linked obesity to the onset of puberty, while its causality and
the potential metabolite mediators remain unclear. We employed a two-sample Mendelian …