[HTML][HTML] Ecological and functional roles of bacteriophages in contrasting environments: marine, terrestrial and human gut

TL Brown, OJ Charity, EM Adriaenssens - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Phages are abundant within ecosystems, but their role is often understated.•
Ecological success models can help explain observed phage–bacteria …

Intestinal phages interact with bacteria and are involved in human diseases

H Shuwen, D Kefeng - Gut Microbes, 2022 - Taylor & Francis
Phages are the most abundant and diverse biological entities on Earth and exert specific
effects on bacterial hosts. The coexistence of phages and bacteria in the intestinal tract is …

Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum

ME Chriswell, AR Lefferts, MR Clay, AR Hsu… - Science translational …, 2022 - science.org
The mucosal origins hypothesis of rheumatoid arthritis (RA) proposes a central role for
mucosal immune responses in the initiation or perpetuation of the systemic autoimmunity …

[HTML][HTML] Gut microbiota in pre-clinical rheumatoid arthritis: From pathogenesis to preventing progression

L Lin, K Zhang, Q Xiong, J Zhang, B Cai, Z Huang… - Journal of …, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive
polyarthritis that leads to cartilage and bone damage. Pre-clinical RA is a prolonged state …

Benzo [a] pyrene stress impacts adaptive strategies and ecological functions of earthworm intestinal viromes

R Xia, M Sun, JL Balcázar, P Yu, F Hu… - The ISME …, 2023 - academic.oup.com
The earthworm gut virome influences the structure and function of the gut microbiome, which
in turn influences worm health and ecological functions. However, despite its ecological and …

Microbiota dysbiosis in primary Sjögren's syndrome and the ameliorative effect of hydroxychloroquine

X Wang, K Pang, J Wang, B Zhang, Z Liu, S Lu, X Xu… - Cell Reports, 2022 - cell.com
The human microbiome plays an important role in autoimmune diseases. However, there is
limited knowledge regarding the microbiota in individuals with primary Sjögren's syndrome …

Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease

Y Tomofuji, T Kishikawa, Y Maeda, K Ogawa… - Annals of the …, 2022 - ard.bmj.com
Objective The relationship between autoimmune diseases and the gut microbiome has been
intensively studied, and several autoimmunity-associated bacterial taxa have been …

Transplantation of bacteriophages from ulcerative colitis patients shifts the gut bacteriome and exacerbates the severity of DSS colitis

A Sinha, Y Li, MK Mirzaei, M Shamash, R Samadfam… - Microbiome, 2022 - Springer
Abstract Background Inflammatory bowel diseases (IBDs) including Crohn's disease (CD)
and ulcerative colitis (UC) are characterized by chronic and debilitating gut inflammation …

Chronic cold environment regulates rheumatoid arthritis through modulation of gut microbiota-derived bile acids

J Liu, F Peng, H Cheng, D Zhang, Y Zhang… - Science of The Total …, 2023 - Elsevier
The pathologies of many diseases are influenced by environmental temperature. As early as
the classical Roman age, people believed that exposure to cold weather was bad for …

Virus genomics: what is being overlooked?

K Kieft, K Anantharaman - Current opinion in virology, 2022 - Elsevier
Viruses are diverse biological entities that influence all life. Even with limited genome sizes,
viruses can manipulate, drive, steal from, and kill their hosts. The field of virus genomics …