[HTML][HTML] Advances in polymeric colloids for cancer treatment

I Ali, SH Althakfi, M Suhail, M Locatelli, MF Hsieh… - Polymers, 2022 - mdpi.com
Polymer colloids have remarkable features and are gaining importance in many areas of
research including medicinal science. Presently, the innovation of cancer drugs is at the top …

[HTML][HTML] Sex differences in colorectal cancer: with a focus on sex hormone–gut microbiome axis

Z Wu, Y Huang, R Zhang, C Zheng, F You… - Cell Communication and …, 2024 - Springer
Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer
(CRC), with men generally exhibiting a slightly higher incidence than women. Research …

[HTML][HTML] Effect of miR-34a on the expression of clock and clock-controlled genes in DLD1 and Lovo human cancer cells with different backgrounds with respect to p53 …

R Moravčík, S Olejárová, J Zlacká, I Herichová - Plos one, 2023 - journals.plos.org
The small non-coding RNA miR-34a is a p53-regulated miRNA that acts as a tumour
suppressor of colorectal cancer (CRC). Oncogenesis is also negatively influenced by …

Discovery and optimization of 2, 3-diaryl-1, 3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity

AM Shawky, FA Almalki, AN Abdalla… - European Journal of …, 2023 - Elsevier
Several studies have indicated the potential therapeutic outcomes of combining selective
COX-2 inhibitors with tubulin-targeting anticancer agents. In the current study, a novel series …

[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

B Refaat, A Aslam, S Idris, AH Almalki… - Frontiers in …, 2023 - frontiersin.org
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

[HTML][HTML] Association between blood lipid levels and risk of gastric cancer: A systematic review and meta-analysis

S Xu, Y Fan, Y Tan, L Zhang, X Li - Plos one, 2023 - journals.plos.org
Objective The association between blood lipid levels and the risk of gastric cancer (GC) is
well known. Therefore, to clarify this association, all relevant prospective cohort studies were …

[HTML][HTML] Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death …

Y Kametani, R Ito, S Ohshima, Y Manabe… - Frontiers in …, 2023 - frontiersin.org
Immune checkpoint inhibitors highlight the importance of anticancer immunity. However,
their clinical utility and safety are limited by the low response rates and adverse effects. We …

[HTML][HTML] Progesterone receptor potentiates macropinocytosis through CDC42 in pancreatic ductal adenocarcinoma

YN Liao, YZ Gai, LH Qian, H Pan, YF Zhang, P Li… - Oncogenesis, 2024 - nature.com
Endocrine receptors play an essential role in tumor metabolic reprogramming and represent
a promising therapeutic avenue in pancreatic ductal adenocarcinoma (PDAC). PDAC is …

[HTML][HTML] Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment

L Wenxuan, L Liu, L Zhang, Z Qiu, Z Wu… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Objective To understand the relationship between steroid hormones synthesized by the
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …

[PDF][PDF] Research progress on the biological basis of Traditional Chinese Medicine syndromes of gastrointestinal cancers

T Guo, S Zhao, W Zhu, H Zhou, H Cheng - Heliyon, 2023 - cell.com
Abstract Gastrointestinal cancers account for 11.6% of all cancers, and are the second most
frequently diagnosed type of cancer worldwide. Traditional Chinese medicine (TCM) …