Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Endothelial cells control vascular tone by releasing nitric oxide (NO) produced by
endothelial NO synthase. The activity of endothelial NO synthase is modulated by the …

In normal vascular physiology, NO plays a key role to maintain the vascular wall in a
quiescent state by inhibition of inflammation, cellular proliferation, and thrombosis. This is in …

This e-book will review special features of the cerebral circulation and how they contribute to
the physiology of the brain. It describes structural and functional properties of the cerebral …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

Aerobic exercise training leads to cardiovascular changes that markedly increase aerobic
power and lead to improved endurance performance. The functionally most important …

Deployment of drug-eluting stents instead of bare-metal stents has dramatically reduced
restenosis rates, but rates of very late stent thrombosis (> 1 year postimplantation) have …

Hawthorn (Crataegus oxyacantha) is a widely used Chinese herb for treatment of
gastrointestinal ailments and heart problems and consumed as food. In North America, the …

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

Endothelium‐dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in
small resistance arteries and thus an important modulator of blood pressure and flow. As the …