Patient-derived tumor spheroid-induced angiogenesis preclinical platform for exploring therapeutic vulnerabilities in cancer

J Ko, S Hyung, YJ Heo, S Jung, ST Kim, SH Park… - Biomaterials, 2024 - Elsevier
This study addresses the demand for research models that can support patient-treatment
decisions and clarify the complexities of a tumor microenvironment by developing an …

High‐Scale 3D‐Bioprinting Platform for the Automated Production of Vascularized Organs‐on‐a‐Chip

A Fritschen, N Lindner, S Scholpp… - Advanced …, 2024 - Wiley Online Library
Abstract 3D bioprinting possesses the potential to revolutionize contemporary
methodologies for fabricating tissue models employed in pharmaceutical research and …

RGD-coated polymeric microbubbles promote ultrasound-mediated drug delivery in an inflamed endothelium-pericyte co-culture model of the blood-brain barrier

C Hark, J Chen, J Blöck, EM Buhl… - Drug Delivery and …, 2024 - Springer
Drug delivery to central nervous pathologies is compromised by the blood-brain barrier
(BBB). A clinically explored strategy to promote drug delivery across the BBB is …

Porous collagen scaffolds enable endothelial lumen formation in vitro under both static and dynamic growth conditions

L Rössler, R Nasehi, N Hansen… - Journal of Biomedical …, 2024 - Wiley Online Library
Despite recent advances in the field of tissue engineering, the development of complex
tissue‐like structures in vitro is compromised by the lack of integration of a functioning …

Evolution of biofabrication and 3D-bioprinting technologies–from market pull to technology push

A Blaeser - at-Automatisierungstechnik, 2024 - degruyter.com
Biofabrication is a biomedical key technology for the cultivation of living tissue structures.
Here, living cells are embedded in a hydrogel matrix and joined using various processes (eg …

[引用][C] Modular formation of in vitro tumor models for oncological research/therapeutic drug screening

W Wang, H Wang - 2024 - Elsevier