Novel therapeutic approaches against acetaminophen-induced liver injury and acute liver failure
Liver injury and acute liver failure caused by acetaminophen (APAP, N-acetyl-p-
aminophenol, paracetamol) overdose is a significant clinical problem in most western …
aminophenol, paracetamol) overdose is a significant clinical problem in most western …
[HTML][HTML] Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, which is safe at
therapeutic doses but can cause severe liver injury and even liver failure after overdoses …
therapeutic doses but can cause severe liver injury and even liver failure after overdoses …
Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation
H Li, Q Weng, S Gong, W Zhang, J Wang, Y Huang… - Food & Function, 2023 - pubs.rsc.org
Acetaminophen (APAP)-induced liver injury (AILI) has become a growing public health
problem. Ferroptosis, an iron-dependent form of cell death associated with lipid peroxide …
problem. Ferroptosis, an iron-dependent form of cell death associated with lipid peroxide …
Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice
Acetaminophen (APAP) overdose is the leading cause of acute liver failure in western
countries. APAP can cause extensive hepatocellular necrosis, which triggers an …
countries. APAP can cause extensive hepatocellular necrosis, which triggers an …
[HTML][HTML] Effects of nerol on paracetamol-induced liver damage in Wistar albino rats
Nerol, a monoterpene is evident to possess diverse biological activities, including
antioxidant, anti-microbial, anti-spasmodic, anthelmintic, and anti-arrhythmias. This study …
antioxidant, anti-microbial, anti-spasmodic, anthelmintic, and anti-arrhythmias. This study …
Protective effects of naringin against drugs and chemical toxins induced hepatotoxicity: a review
The liver is a vital metabolic organ for drug and xenobiotic metabolism which is influenced
by chemical and natural toxins. Liver injury is associated with systemic oxidative stress …
by chemical and natural toxins. Liver injury is associated with systemic oxidative stress …
Plant natural products for human health
The aim of this Special Issue on “Plant Natural Products for Human Health” is to compile a
series of scientific reports to demonstrate the medicinal potential of plant natural products …
series of scientific reports to demonstrate the medicinal potential of plant natural products …
Sterols and triterpenes: Antiviral potential supported by in-silico analysis
The acute respiratory syndrome caused by the novel coronavirus (SARS-CoV-2) caused
severe panic all over the world. The coronavirus (COVID-19) outbreak has already brought …
severe panic all over the world. The coronavirus (COVID-19) outbreak has already brought …
Acetaminophen induced hepatotoxicity: An overview of the promising protective effects of natural products and herbal formulations
Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …
From function to metabolome: Metabolomic analysis reveals the effect of probiotic fermentation on the chemical compositions and biological activities of perilla …
Z Wang, X Jin, X Zhang, X Xie, Z Tu, X He - Frontiers in nutrition, 2022 - frontiersin.org
This study aimed to investigate the impact of probiotic fermentation on the active
components and functions of Perilla frutescens leaves (PFL). PFL was fermented for 7 days …
components and functions of Perilla frutescens leaves (PFL). PFL was fermented for 7 days …