[HTML][HTML] The role of DNA methylation in epigenetics of aging

A Unnikrishnan, WM Freeman, J Jackson… - Pharmacology & …, 2019 - Elsevier
Recent research suggests that epigenetics, especially DNA methylation, plays a mechanistic
role in aging. Epigenetic clocks, which measure changes in a few hundred specific CpG …

Dietary compounds as epigenetic modulating agents in cancer

Á Carlos-Reyes, JS López-González… - Frontiers in …, 2019 - frontiersin.org
Epigenetic mechanisms control gene expression during normal development and their
aberrant regulation may lead to human diseases including cancer. Natural phytochemicals …

DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation

I Rauluseviciute, F Drabløs, MB Rye - BMC medical genomics, 2020 - Springer
Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …

In-silico analysis of cis-acting regulatory elements of pathogenesis-related proteins of Arabidopsis thaliana and Oryza sativa

A Kaur, PK Pati, AM Pati, AK Nagpal - PloS one, 2017 - journals.plos.org
Pathogenesis related (PR) proteins are low molecular weight family of proteins induced in
plants under various biotic and abiotic stresses. They play an important role in plant-defense …

Quantum scale organic semiconductors for SERS detection of DNA methylation and gene expression

S Ganesh, K Venkatakrishnan, B Tan - Nature communications, 2020 - nature.com
Cancer stem cells (CSC) can be identified by modifications in their genomic DNA. Here, we
report a concept of precisely shrinking an organic semiconductor surface-enhanced Raman …

MethylSig: a whole genome DNA methylation analysis pipeline

Y Park, ME Figueroa, LS Rozek, MA Sartor - Bioinformatics, 2014 - academic.oup.com
Motivation: DNA methylation plays critical roles in gene regulation and cellular specification
without altering DNA sequences. The wide application of reduced representation bisulfite …

The role of DNA methylation in ageing and cancer

AE Morgan, TJ Davies, MT Mc Auley - Proceedings of the Nutrition …, 2018 - cambridge.org
The aim of the present review paper is to survey the literature related to DNA methylation,
and its association with cancer and ageing. The review will outline the key factors, including …

Molecular biomarkers for gestational diabetes mellitus

S Dias, C Pheiffer, Y Abrahams, P Rheeder… - International journal of …, 2018 - mdpi.com
Gestational diabetes mellitus (GDM) is a growing public health problem worldwide. The
condition is associated with perinatal complications and an increased risk for future …

Epigenetics of SFRP1: The Dual Roles in Human Cancers

R Baharudin, FYF Tieng, LH Lee, NS Ab Mutalib - Cancers, 2020 - mdpi.com
Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …

Maternal prenatal stress and infant DNA methylation: a systematic review

DW Sosnowski, C Booth, TP York… - Developmental …, 2018 - Wiley Online Library
Maternal prenatal stress has been linked to a variety of infant postnatal outcomes, partially
through alterations in fetal HPA axis functioning; yet the underlying pathobiology remains …