[HTML][HTML] The role of vaccines in combatting antimicrobial resistance

F Micoli, F Bagnoli, R Rappuoli, D Serruto - Nature Reviews …, 2021 - nature.com
The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

Human organoids: tools for understanding biology and treating diseases

F Schutgens, H Clevers - Annual Review of Pathology …, 2020 - annualreviews.org
Organoids are in vitro–cultured three-dimensional structures that recapitulate key aspects of
in vivo organs. They can be established from pluripotent stem cells and from adult stem …

DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data

G Arango-Argoty, E Garner, A Pruden, LS Heath… - Microbiome, 2018 - Springer
Background Growing concerns about increasing rates of antibiotic resistance call for
expanded and comprehensive global monitoring. Advancing methods for monitoring of …

Drug resistant Tuberculosis: A review

JL Khawbung, D Nath, S Chakraborty - … immunology, microbiology and …, 2021 - Elsevier
Tuberculosis (TB) was announced as a global emergency in 1993. There was an alarming
counter attack of TB worldwide. However, when it was known that TB can be cured …

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

KD Mayer-Barber, BB Andrade, SD Oland, EP Amaral… - Nature, 2014 - nature.com
Tuberculosis remains second only to HIV/AIDS as the leading cause of mortality worldwide
due to a single infectious agent. Despite chemotherapy, the global tuberculosis epidemic …

Resistencia bacteriana a los antibióticos: una crisis global

JI Alós - Enfermedades infecciosas y microbiología clínica, 2015 - Elsevier
La introducción de los antibióticos en la práctica clínica supuso una de las intervenciones
más importantes para el control de las enfermedades infecciosas. Los antibióticos han …

[HTML][HTML] National survey of drug-resistant tuberculosis in China

Y Zhao, S Xu, L Wang, DP Chin, S Wang… - … England Journal of …, 2012 - Mass Medical Soc
Background The available information on the epidemic of drug-resistant tuberculosis in
China is based on local or regional surveys. In 2007, we carried out a national survey of …

The challenge of new drug discovery for tuberculosis

A Koul, E Arnoult, N Lounis, J Guillemont, K Andries - Nature, 2011 - nature.com
Tuberculosis (TB) is more prevalent in the world today than at any other time in human
history. Mycobacterium tuberculosis, the pathogen responsible for TB, uses diverse …

[PDF][PDF] Crystal structures of membrane transporter MmpL3, an anti-TB drug target

B Zhang, J Li, X Yang, L Wu, J Zhang, Y Yang, Y Zhao… - Cell, 2019 - cell.com
Despite intensive efforts to discover highly effective treatments to eradicate tuberculosis
(TB), it remains as a major threat to global human health. For this reason, new TB drugs …

Emerging frontiers of deep eutectic solvents in drug discovery and drug delivery systems

MH Zainal-Abidin, M Hayyan, GC Ngoh… - Journal of controlled …, 2019 - Elsevier
The applications of eutectic systems, including deep eutectic solvents (DESs), in diverse
sectors have drawn significant interest from researchers, academicians, engineers, medical …