[HTML][HTML] Research advances for virus-vectored tuberculosis vaccines and latest findings on tuberculosis vaccine development

Z Hu, SH Lu, DB Lowrie, XY Fan - Frontiers in Immunology, 2022 - frontiersin.org
Tuberculosis (TB), caused by respiratory infection with Mycobacterium tuberculosis, remains
a major global health threat. The only licensed TB vaccine, the one-hundred-year-old Bacille …

[HTML][HTML] When a neglected tropical disease goes global: knowledge, attitudes and practices of Italian physicians towards monkeypox, preliminary results

M Riccò, P Ferraro, V Camisa, E Satta… - Tropical medicine and …, 2022 - mdpi.com
Monkeypox (MPX) has been regarded as a neglected tropic disease of Western and Central
Africa since the early 70s. However, during May 2022, an unprecedent outbreak of MPX has …

Recent advances in respiratory immunization: A focus on COVID-19 vaccines

X He, X Chen, H Wang, G Du, X Sun - Journal of Controlled Release, 2023 - Elsevier
The development of vaccines has always been an essential task worldwide since vaccines
are regarded as powerful weapons in protecting the global population. Although the vast …

[HTML][HTML] Development of modified vaccinia virus ankara-based vaccines: advantages and applications

OV Orlova, DV Glazkova, EV Bogoslovskaya… - Vaccines, 2022 - mdpi.com
Modified vaccinia virus Ankara (MVA) is a promising viral vector for vaccine development.
MVA is well studied and has been widely used for vaccination against smallpox in Germany …

[HTML][HTML] Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant

N Yang, A Garcia, C Meyer, T Tuschl, T Merghoub… - npj Vaccines, 2022 - nature.com
Protein or peptide-based subunit vaccines have generated excitement and renewed interest
in combating human cancer or COVID-19 outbreak. One major concern for subunit vaccine …

[HTML][HTML] Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines

I del Moral-Sánchez, EG Wee, Y Xian, WH Lee… - npj Vaccines, 2024 - nature.com
Recombinant native-like HIV-1 envelope glycoprotein (Env) trimers are used in candidate
vaccines aimed at inducing broadly neutralizing antibodies. While state-of-the-art SOSIP or …

[HTML][HTML] Cross-reactive antibody response to Monkeypox virus surface proteins in a small proportion of individuals with and without Chinese smallpox vaccination …

A Xia, X Wang, J He, W Wu, W Jiang, S Xue, Q Zhang… - BMC biology, 2023 - Springer
Background After the eradication of smallpox in China in 1979, vaccination with the vaccinia
virus (VACV) Tiantan strain for the general population was stopped in 1980. As the …

[HTML][HTML] Evaluating immunogenicity of pathogen-derived T-cell epitopes to design a peptide-based smallpox vaccine

HQ Quach, IG Ovsyannikova, GA Poland… - Scientific reports, 2022 - nature.com
Despite the eradication in 1980, developing safe and effective smallpox vaccines remains
an active area of research due to the recent outbreaks and the public health concern that …

[HTML][HTML] Utilization of viral vector vaccines in preparing for future pandemics

KA Hofmeyer, KM Bianchi, DN Wolfe - Vaccines, 2022 - mdpi.com
As the global response to COVID-19 continues, government stakeholders and private
partners must keep an eye on the future for the next emerging viral threat with pandemic …

[HTML][HTML] Orthopoxvirus Zoonoses—Do We Still Remember and Are Ready to Fight?

M Gieryńska, L Szulc-Dąbrowska, J Struzik… - Pathogens, 2023 - mdpi.com
The eradication of smallpox was an enormous achievement due to the global vaccination
program launched by World Health Organization. The cessation of the vaccination program …