Oxidative stress in amyotrophic lateral sclerosis: pathophysiology and opportunities for pharmacological intervention
T Cunha-Oliveira, L Montezinho… - Oxidative medicine …, 2020 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot
disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to …
disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to …
Role of nuclear factor kappa B (NF-κB) signalling in neurodegenerative diseases: an mechanistic approach
S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …
biological activity via binding to a promoter region in the nucleus and transcribing various …
Nearly 30 years of animal models to study amyotrophic lateral sclerosis: a historical overview and future perspectives
T Bonifacino, RA Zerbo, M Balbi, C Torazza… - International journal of …, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal, multigenic, multifactorial, and non-cell
autonomous neurodegenerative disease characterized by upper and lower motor neuron …
autonomous neurodegenerative disease characterized by upper and lower motor neuron …
[HTML][HTML] Masitinib: The promising actor in the next season of the Amyotrophic Lateral Sclerosis treatment series
Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with high
mortality and morbidity rate affecting both upper and lower motor neurons (MN). Muscle …
mortality and morbidity rate affecting both upper and lower motor neurons (MN). Muscle …
Parenteral microemulsion for drug delivery: Advances and update
Patients with chronic conditions often need to adhere to long-term medication regimens,
requiring them to take medication daily for an extended period. Nevertheless, the …
requiring them to take medication daily for an extended period. Nevertheless, the …
[HTML][HTML] Advances in nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a
progressive neurodegenerative disease that affects both upper and lower motor neurons …
progressive neurodegenerative disease that affects both upper and lower motor neurons …
The global economic impact of neurodegenerative diseases: Opportunities and challenges
W Zahra, SN Rai, H Birla, SS Singh, H Dilnashin… - Bioeconomy for …, 2020 - Springer
The main challenge in today's world to the healthcare system is the elevated occurrence of
the neurodegenerative disorders. Progress in the field of bioinformatics and biomedical …
the neurodegenerative disorders. Progress in the field of bioinformatics and biomedical …
The role of the microbiota–gut–brain axis and antibiotics in ALS and neurodegenerative diseases
M Obrenovich, H Jaworski, T Tadimalla, A Mistry… - Microorganisms, 2020 - mdpi.com
The human gut hosts a wide and diverse ecosystem of microorganisms termed the
microbiota, which line the walls of the digestive tract and colon where they co-metabolize …
microbiota, which line the walls of the digestive tract and colon where they co-metabolize …
A state of the art of antioxidant properties of curcuminoids in neurodegenerative diseases
S Silvestro, C Sindona, P Bramanti… - International Journal of …, 2021 - mdpi.com
Neurodegenerative diseases represent a set of pathologies characterized by an irreversible
and progressive, and a loss of neuronal cells in specific areas of the brain. Oxidative …
and progressive, and a loss of neuronal cells in specific areas of the brain. Oxidative …
Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes
C Torazza, F Provenzano, E Gallia, M Cerminara… - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive degeneration of motor neurons (MNs). Astrocytes display a toxic phenotype in …
progressive degeneration of motor neurons (MNs). Astrocytes display a toxic phenotype in …