This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Cardiovascular disease (CVD) is a serious health challenge, causing more deaths
worldwide than cancer. The vascular endothelium, which forms the inner lining of blood …

Mechanical cues in the cell microenvironment such as those from extracellular matrix
properties, stretching, compression and shear stress, play a critical role in maintaining …

Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …

Atherosclerosis is the leading cause of death worldwide and leukocyte recruitment is a key
element of this phenomenon, thus allowing immune cells to enter the arterial wall. There, in …

The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

Therapeutic ultrasound has been studied for over seven decades for different medical
applications. The versatility of ultrasound applications are highly dependent on the …

Biophysical and biochemical cues work in concert to regulate angiogenesis. These cues
guide angiogenesis during development and wound healing. Abnormal cues contribute to …

Vascular smooth muscle cells (SMCs) are circumferentially oriented perpendicular to the
blood vessel and maintain the contractile phenotype in physiological conditions. They can …

Blood vessels expand via sprouting angiogenesis, and this process involves numerous
endothelial cell behaviors, such as collective migration, proliferation, cell–cell junction …