[HTML][HTML] Mitochondrial regulation of ferroptosis in cancer therapy
X Cheng, J Zhang, Y Xiao, Z Wang, J He, M Ke… - International Journal of …, 2023 - mdpi.com
Ferroptosis, characterized by glutamate overload, glutathione depletion, and
cysteine/cystine deprivation during iron-and oxidative-damage-dependent cell death, is a …
cysteine/cystine deprivation during iron-and oxidative-damage-dependent cell death, is a …
Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion
LJ Tang, XJ Luo, H Tu, H Chen, XM Xiong… - Naunyn-Schmiedeberg's …, 2021 - Springer
Ferroptosis is an iron-dependent regulated necrosis. This study aims to evaluate the
contribution of ferroptosis to ischemia or reperfusion injury, and lay a basis for precise …
contribution of ferroptosis to ischemia or reperfusion injury, and lay a basis for precise …
[HTML][HTML] Copper homeostasis in chronic kidney disease and its crosstalk with ferroptosis
H Jiayi, T Ziyuan, X Tianhua, Z Mingyu, M Yutong… - Pharmacological …, 2024 - Elsevier
Chronic kidney disease (CKD) has become a global public health problem with high
morbidity and mortality. Renal fibrosis can lead to end-stage renal disease (ESRD) …
morbidity and mortality. Renal fibrosis can lead to end-stage renal disease (ESRD) …
Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat
Acute paracetamol (APAP) toxicity is a leading cause of liver, and less commonly renal,
injuries through oxidative stress and inflammation. Albeit vitamin D (VD) is a well-known anti …
injuries through oxidative stress and inflammation. Albeit vitamin D (VD) is a well-known anti …
[HTML][HTML] Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8+ T cells
J Liang, Y Shen, Y Wang, Y Huang, J Wang, Q Zhu… - Molecular Brain, 2022 - Springer
Cerebral malaria is the most serious complication of malaria infection, with 26% of surviving
children having neurological sequelae, which may be caused by neuron damage, but the …
children having neurological sequelae, which may be caused by neuron damage, but the …
Relieving ferroptosis may partially reverse neurodegeneration of the auditory cortex
X Chen, D Li, HY Sun, WW Wang, H Wu… - The FEBS …, 2020 - Wiley Online Library
Central presbycusis is caused by degradation of the auditory centre during ageing. Its main
characteristics are difficulties in understanding language and localizing sound. Presbycusis …
characteristics are difficulties in understanding language and localizing sound. Presbycusis …
[HTML][HTML] In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the …
Simple Summary Failure of chemotherapy is common during the treatment of colon cancer,
and there is a compelling need to develop alternative therapeutic approaches against this …
and there is a compelling need to develop alternative therapeutic approaches against this …
[HTML][HTML] Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males
Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …
Role of the SLC22A17/lipocalin-2 receptor in renal endocytosis of proteins/metalloproteins: A focus on iron-and cadmium-binding proteins
F Thévenod, R Herbrechter… - American Journal …, 2023 - journals.physiology.org
The transmembrane protein SLC22A17 [or the neutrophil gelatinase-associated
lipocalin/lipocalin-2 (LCN2)/24p3 receptor] is an atypical member of the SLC22 family of …
lipocalin/lipocalin-2 (LCN2)/24p3 receptor] is an atypical member of the SLC22 family of …
Protective activities of ellagic acid and urolithins against kidney toxicity of environmental pollutants: A review
WR García-Niño, L Ibarra-Lara… - Environmental …, 2022 - Elsevier
Oxidative stress and inflammation are two possible mechanisms related to nephrotoxicity
caused by environmental pollutants. Ellagic acid, a powerful antioxidant phytochemical, may …
caused by environmental pollutants. Ellagic acid, a powerful antioxidant phytochemical, may …