[HTML][HTML] Type 2 inflammation in eosinophilic esophagitis: from pathophysiology to therapeutic targets

F Racca, G Pellegatta, G Cataldo, E Vespa… - Frontiers in …, 2022 - frontiersin.org
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …

Eosinophilic esophagitis: pathophysiology and definition

F Clayton, K Peterson - Gastrointestinal Endoscopy Clinics, 2018 - giendo.theclinics.com
Eosinophilic esophagitis (EoE) is an adaptive immune response to patient-specific antigens,
mostly foods. EoE is not IgE-mediated and is instead likely mediated by Th2 lymphocytes …

Development and validation of a mucosal impedance contour analysis system to distinguish esophageal disorders

DA Patel, T Higginbotham, JC Slaughter, M Aslam… - Gastroenterology, 2019 - Elsevier
Background & Aims Diagnostic testing for chronic esophageal disorders relies on
histopathology analysis of biopsies or uncomfortable transnasal catheters or wireless pH …

Untangling nonerosive reflux disease from functional heartburn

D Patel, R Fass, M Vaezi - Clinical Gastroenterology and Hepatology, 2021 - Elsevier
Heartburn is a common symptom in clinical practice, but as many as 70% of patients have
normal findings from upper endoscopy. Most of these patients have nonerosive reflux …

Mucosal impedance: a new approach to diagnosing gastroesophageal reflux disease and eosinophilic esophagitis

C Barrett, Y Choksi, MF Vaezi - Current gastroenterology reports, 2018 - Springer
Abstract Purpose of Review In this review, we discuss current diagnostic testing modalities
for both gastroesophageal reflux disease (GERD) and eosinophilic esophagitis (EoE) and …

New developments in the diagnosis and treatment of eosinophilic esophagitis

QM Nhu, FJ Moawad - Current treatment options in gastroenterology, 2019 - Springer
Purpose of review Eosinophilic esophagitis (EoE) is a chronic, allergen-driven, immune-
mediated disease of the esophagus that progresses to esophageal fibrostenosis if left …

[HTML][HTML] Mucosal impedance testing: A new diagnostic testing in gastroesophageal reflux disease

WY Lei, MF Vaezi, RD Naik, CL Chen - Journal of the Formosan Medical …, 2020 - Elsevier
Current diagnostic testing for gastroesophageal reflux disease (GERD) include endoscopy,
ambulatory pH and intraluminal impedance monitoring. However, they are suboptimal and …

Magnetic sphincter augmentation is an effective treatment for atypical symptoms caused by gastroesophageal reflux disease

MA Ward, A Ebrahim, J Kopita, L Arviso, GO Ogola… - Surgical …, 2020 - Springer
Background The purpose of this study was to determine whether magnetic sphincter
augmentation (MSA) could effectively treat patients with gastroesophageal reflux disease …

Optimizing ambulatory reflux monitoring: current findings and future directions

D Dasarathy, M Vaezi, D Patel - Expert Review of Gastroenterology …, 2024 - Taylor & Francis
Introduction Gastroesophageal reflux disease (GERD) is the most common diagnosis seen
in outpatient gastroenterology clinics. The diagnosis is made by a variable combination of …

Mucosal impedance for esophageal disease: evaluating the evidence

JO Clarke, NK Ahuja, WW Chan… - Annals of the New …, 2020 - Wiley Online Library
Impedance has traditionally been employed in esophageal disease as a means to assess
bolus flow and reflux episodes. Recent and ongoing research has provided new and novel …