The melanin pigments eumelanin (EM) and pheomelanin (PM), which are dark brown to
black and yellow to reddish-brown, respectively, are widely found among vertebrates. They …

Tyrosinase is a copper-containing enzyme which is widely distributed in nature (eg, bacteria,
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …

The noradrenergic locus coeruleus (LC) is among the first regions of the brain affected by
pathology in both Alzheimer's disease (AD) and Parkinson's disease (PD), but the reasons …

A biomarker for declined methylation capacity is elevation of homocysteine levels. They
increase the risk for onset of vascular disease and contribute to progression of chronic …

The author identified the genes and proteins of human enzymes involved in the biosynthesis
of catecholamines (dopamine, norepinephrine, epinephrine) and tetrahydrobiopterin (BH4) …

Parkinson's disease (PD) represents the second most widespread neurodegenerative
disease, and early monitoring and diagnosis are urgent at present. Tyrosine hydroxylase …

Our and other's laboratory microarray-derived transcriptomic studies in human PD
substantia nigra pars compacta (SNpc) samples have opened an avenue to concentrate on …

Currently, there is no effective treatment for Parkinson's disease (PD), and the regenerative
treatment of neural stem cells (NSCs) is considered the most promising method. This study …

Melanin and the process of melanin synthesis or melanogenesis have central roles in the
immune system of insects, and production of melanin-synthesizing enzymes from their …

Simple Summary This article examines the fascinating association between melanoma, a
malignant skin cancer, and Parkinson's disease (PD), a neurodegenerative disorder. Both …