The role of NLRP3 inflammasome in cerebrovascular diseases pathology and possible therapeutic targets
R Bai, Y Lang, J Shao, Y Deng, R Refuhati… - ASN neuro, 2021 - journals.sagepub.com
Cerebrovascular diseases are pathological conditions involving impaired blood flow in the
brain, primarily including ischaemic stroke, intracranial haemorrhage, and subarachnoid …
brain, primarily including ischaemic stroke, intracranial haemorrhage, and subarachnoid …
Natural products modulate cell apoptosis: A promising way for the treatment of ulcerative colitis
C Liu, Y Zeng, Y Wen, X Huang, Y Liu - Frontiers in pharmacology, 2022 - frontiersin.org
Ulcerative colitis (UC) is a chronic inflammatory bowel disease impacting patients' quality of
life and imposing heavy societal and economic burdens. Apoptosis of intestinal epithelial …
life and imposing heavy societal and economic burdens. Apoptosis of intestinal epithelial …
Caffeic acid supplement alleviates colonic inflammation and oxidative stress potentially through improved gut microbiota community in mice
F Wan, R Zhong, M Wang, Y Zhou, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Caffeic acid (CA) is one of the major phenolic acids of coffee with multiple biological
activities. Our previous study found that 500 mg/kg of chlorogenic acid (CGA) had the …
activities. Our previous study found that 500 mg/kg of chlorogenic acid (CGA) had the …
Thyme (Thymus vulgaris L.) polyphenols ameliorate DSS-induced ulcerative colitis of mice by mitigating intestinal barrier damage, regulating gut microbiota, and …
Z Zhou, W He, H Tian, P Zhan, J Liu - Food & function, 2023 - pubs.rsc.org
Thyme (Thymus vulgaris L.) is an important medicinal and edible homologous plant, and the
composition and bioactivity of its polyphenol extracts have attracted widespread attention …
composition and bioactivity of its polyphenol extracts have attracted widespread attention …
Ferulic acid ameliorates ulcerative colitis in a rat model via the inhibition of two LPS-TLR4-NF-κB and NF-κB-INOS-NO signaling pathways and thus alleviating the …
M Ghasemi-Dehnoo, H Amini-Khoei, Z Lorigooini… - …, 2023 - Springer
Introduction Ulcerative colitis is a chronic inflammation of the colon. However, the common
treatment for it is accompanied by many complications. Therefore, the present study was …
treatment for it is accompanied by many complications. Therefore, the present study was …
Supplementation With Chinese Medicinal Plant Extracts From Lonicera hypoglauca and Scutellaria baicalensis Mitigates Colonic Inflammation by Regulating …
F Wan, M Wang, R Zhong, L Chen, H Han… - Frontiers in cellular …, 2022 - frontiersin.org
Colitis, a chronic inflammatory bowel disease, is characterized by bloody diarrhea and
inflammation in the colon. Lonicera hypoglauca (“Shanyinhua” in Chinese) and Scutellaria …
inflammation in the colon. Lonicera hypoglauca (“Shanyinhua” in Chinese) and Scutellaria …
Discoidin domain receptor 1 (DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis
X Li, Q Li, B Xiong, H Chen, X Wang, D Zhang - Pharmacological Research, 2022 - Elsevier
Background and aims Discoidin domain receptor 1 (DDR1) encodes a receptor tyrosine
kinase involved in multiple physiological and pathological processes. DDR1 is expressed in …
kinase involved in multiple physiological and pathological processes. DDR1 is expressed in …
[HTML][HTML] Flavonoids and saponins: What have we got or missed?
Background Flavonoids and saponins are important bioactive compounds that have
attracted wide research interests. This review aims to summarise the state of the art of the …
attracted wide research interests. This review aims to summarise the state of the art of the …
Epigallocatechin gallate alleviates staphylococcal enterotoxin a-induced intestinal barrier damage by regulating gut microbiota and inhibiting the TLR4-NF-κB/MAPKs …
C Liu, J Liu, W Wang, M Yang, K Chi… - Journal of Agricultural …, 2023 - ACS Publications
Natural phytochemicals have attracted increasing attention because of their promising ability
to tackle bacteriotoxin-induced public safety concerns. However, it is unclear how natural …
to tackle bacteriotoxin-induced public safety concerns. However, it is unclear how natural …
[HTML][HTML] Arjunolic acid protects the intestinal epithelial barrier, ameliorating Crohn's disease-like colitis by restoring gut microbiota composition and inactivating TLR4 …
Z Zhang, L Zuo, X Song, L Wang, Y Zhang, Y Cheng… - Phytomedicine, 2024 - Elsevier
Abstract Background and Aims Crohn's disease (CD) is characterized by an overabundance
of epithelial cell death and an imbalance in microflora, both of which contribute to the …
of epithelial cell death and an imbalance in microflora, both of which contribute to the …