ABSTRACT RNA therapeutics comprise a diverse group of oligonucleotide-based drugs
such as antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and short …

Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …

Duchenne muscular dystrophy is caused by the loss of functional dystrophin that secondarily
causes systemic metabolic impairment in skeletal muscles and cardiomyocytes. The …

Sarcalumenin (SAR) is a luminal Ca2+ buffer protein with high capacity but low affinity for
calcium binding found predominantly in the longitudinal sarcoplasmic reticulum (SR) of fast …

Duchenne muscular dystrophy (DMD) is a progressive hereditary disease caused by the
absence of the dystrophin protein. This is secondarily accompanied by a dysregulation of …

Duchenne muscular dystrophy (DMD) is caused by loss-of-function mutations in the
dystrophin gene on chromosome Xp21. Disruption of the dystrophin–glycoprotein complex …

Duchenne muscular dystrophy (DMD) is a striated muscle degenerative disease due to loss
of functional dystrophin protein. Loss of dystrophin results in susceptibility of muscle …

Dystrophin-deficient muscular dystrophy (Duchenne dystrophy) is characterized by impaired
ion homeostasis, in which mitochondria play an important role. In the present work, using a …

Skeletal muscle is the protein reservoir of our body and an important regulator of glucose
and lipid homeostasis. The dystrophin gene is the largest gene and has a key role in …

Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease characterised by severe
muscle wasting. The mechanisms underlying the DMD pathology likely involve the …