A protein (BMP1) was purified from common Indian toad (Bufo melanostictus, Schneider)
skin through DEAE cellulose ion exchange chromatography and high performance liquid …

Abstract Earlier, a protein (BMP1, MW-79kDa) had been isolated from Indian toad (Bufo
melanostictus) skin aqueous extract possessed anticancer activity against EAC bearing …

Parotoid glands of amphibians are known for the production of several biologically active
compounds having pharmacological and toxic effects in mammals. In the present work, a …

As a kind of promising anticancer compounds, the preparation of bufadienolides is a hot
study spot. However, due to the complexity of biological sample, the purification of …

Marinobufagenin is a bufadienolide compound detected mainly in skin and parotoid gland
secretions of Rhinella marina (L.) toad. Bufadienolides regulate the Na+/K+‐ATPase pump …

Background: The resistance against antimalarial drugs represents a global challenge in the
fight and control of malaria. The Brazilian biodiversity can be an important tool for research …

A preocupação em buscar novos fármacos para o tratamento da leishmaniose é cada vez
maior em virtude da toxicidade dos existentes e do aumento da resistência do parasito, o …

Toad skin secretions are a rich source of various biologically active compounds, such as
alkaloids, bufadienolides, biogenic amines, or peptides. Also plants from Hyacinthaceae …

Traditional Chinese medicine (TCM) has been increasingly applied in both preventing and
treating a variety of cancers in the last decades, attributing to its fewer side effects as …

Anuran secretions are rich sources of bioactive molecules, including antimicrobial and
antitumoral compounds. The aims of this study were to investigate the therapeutic potential …