Abstract Three new bufadienolides,(2β, 5β, 14β)-2, 5, 14-trihydroxy-bufa-20, 22-dienolide
(1),(3α, 16β)-3, 16-dihydroxy-bufa-14, 20, 22-trienolide (2) and (3β, 5β, 16α)-3, 5, 16 …

Cinobufacini (Huachansu) injections have been widely used for the treatment of various
cancers in clinical applications in China. As an aqueous extract of the skin of Bufo bufo …

Rhinella icterica is a Brazilian toad with a parotoid secretion that is toxic to insects. In this
work, we examined the entomotoxicity of this secretion in locust (Locusta migratoria) semi …

Malaria, a mosquito-borne disease, is caused by protozoa of the genus Plasmodium and
constitutes a serious public health problem. Because current insecticides used to control …

Toad venom, called as ChanSu in China, is a widely used traditional Chinese medicine
(TCM) whose active components are mainly bufadienolides. ChanSu could exhibit …

Bufadienolide is a kind of natural steroids with significant anti-cancer activities. Hitherto, the
number of structural modification on the bufadienolides has reached more than 100. The …

Resibufogenin (RB), a major bioactive bufadienolide, has the potential anticancer activity. In
the present work, biotransformation of RB by Actinomucor elegans AS 3.2778 yielded five …

A new bufadienolide named dyscinobufotalin (1), along with twenty known bufadienolides (2–
21) were isolated from the venom of Bufo bufo gargarizans. Their structures were elucidated …

The biochemical defense mechanisms of amphibians involve cutaneous secretions of
bioactive molecules with antimicrobial activity. This study evaluated the in vitro activity of …