Cytokines have pivotal roles in immunity, making them attractive as therapeutics for a variety
of immune-related disorders. However, the widespread clinical use of cytokines has been …

In all cells, proteins are continuously synthesized and degraded to maintain protein
homeostasis and modify gene expression levels in response to stimuli. Collectively, the …

Exploration of protein function and interaction is critical for discovering links among
genomics, proteomics, and disease state; yet, the immense complexity of proteomics found …

In the late 70's, the discovery of the restriction enzymes made possible the biological
production of functional proteins by recombinant DNA technologies, a fact that largely …

Endotoxins are the major contributors to the pyrogenic response caused by contaminated
pharmaceutical products, formulation ingredients, and medical devices. Recombinant …

The emergence of neoteric synthetic routes for materials functionalization is an interesting
phenomenon in materials chemistry. In particular, the union of materials chemistry with …

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there
were only 19 biotechology medicines on the market. Currently there are more than 100, with …

Plants offer the tantalizing prospect of low-cost automated manufacturing processes for
biopharmaceutical proteins, but several challenges must be addressed before such goals …

While packed bed chromatography, known as conventional chromatography, has been
serving the biopharmaceutical industry for decades as the bioseparation method of choice …

Antibiotic resistance poses a growing threat to global public health. It is urgent to develop
new alternative antibiotics. Antimicrobial peptide (AMP) is a diverse class of natural …