Platelet adhesion, activation and aggregation on the exposed subendothelial extracellular
matrix (ECM) are essential for haemostasis, but may also lead to occlusion of diseased …

Although platelets are best known for their role in hemostasis, they are also crucial in
development, host defense, inflammation, and tissue repair. Many of these roles are …

Platelets are central mediators of thrombosis and hemostasis. At the site of vascular injury,
platelet accumulation (ie adhesion and aggregation) constitutes the first wave of hemostasis …

Ischaemic stroke is a leading cause of death and disability worldwide. The complex cellular
interactions leading from thromboembolic vessel occlusion to infarct development within the …

C-type lectin-like receptor 2 (CLEC-2, also known as CLEC-1b) is expressed on platelets,
Kupffer cells and other immune cells, and binds to various ligands including the mucin-like …

Platelet activation is a key step in the pathogenesis of ischemic cardio-and cerebrovascular
diseases, which represent the leading causes of death and severe disability worldwide …

Platelets are the main players in thrombotic diseases, where activated platelets not only
mediate thrombus formation but also are involved in multiple interactions with vascular cells …

Human platelets express Fcγ RII a, the low‐affinity receptor for the constant fragment (Fc) of
immunoglobulin (Ig) G that is also found on neutrophils, monocytes, and macrophages …

Subendothelial collagen exposed to platelets after rupture of atherosclerotic plaques is the
main trigger of platelet activation und acute arterial thrombotic occlusion leading to …

Essentials• Relationship of acquired von Willebrand disease (VWD) and platelet dysfunction
is explored.• Patients with ventricular assist devices and on extracorporeal membrane …