Curcumin: an inflammasome silencer

S Hasanzadeh, MI Read, AR Bland, M Majeed… - Pharmacological …, 2020 - Elsevier
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

The role of resveratrol in cancer therapy

JH Ko, G Sethi, JY Um, MK Shanmugam… - International journal of …, 2017 - mdpi.com
Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Polyphenols targeting MAPK mediated oxidative stress and inflammation in rheumatoid arthritis

T Behl, T Upadhyay, S Singh, S Chigurupati… - Molecules, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly
symmetric, which causes joint inflammation, cartilage degeneration and bone erosion …

Oxidative stress and natural antioxidants in osteoporosis: Novel preventive and therapeutic approaches

G Marcucci, V Domazetovic, C Nediani, J Ruzzolini… - Antioxidants, 2023 - mdpi.com
This review reports in detail the cellular and molecular mechanisms which regulate the bone
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …

Resveratrol and cancer: focus on in vivo evidence

LG Carter, JA D'Orazio… - Endocrine-related …, 2014 - erc.bioscientifica.com
Resveratrol is a naturally occurring polyphenol that provides a number of anti-aging health
benefits including improved metabolism, cardioprotection, and cancer prevention. Much of …

Therapeutic effects of curcumin in inflammatory and immune‐mediated diseases: A nature‐made jack‐of‐all‐trades?

E Abdollahi, AA Momtazi, TP Johnston… - Journal of cellular …, 2018 - Wiley Online Library
Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities.
Novel animal and human studies indicate that curcumin can affect different immune cells …

The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis

KY Chin - Drug design, development and therapy, 2016 - Taylor & Francis
Osteoarthritis is a degenerative disease of the joint affecting aging populations worldwide. It
has an underlying inflammatory cause, which contributes to the loss of chondrocytes …

TNF-α and IL-1β modulate blood-brain barrier permeability and decrease amyloid-β peptide efflux in a human blood-brain barrier model

R Versele, E Sevin, F Gosselet, L Fenart… - International journal of …, 2022 - mdpi.com
The blood-brain barrier (BBB) is a selective barrier and a functional gatekeeper for the
central nervous system (CNS), essential for maintaining brain homeostasis. The BBB is …

Curcuminoid treatment for knee osteoarthritis: A randomized double‐blind placebo‐controlled trial

Y Panahi, AR Rahimnia, M Sharafi… - Phytotherapy …, 2014 - Wiley Online Library
Treatment of osteoarthritis (OA) is challenging owing to the inefficacy and long‐term adverse
events of currently available medications including non‐steroidal anti‐inflammatory drugs …