Methamphetamine toxicity and messengers of death

IN Krasnova, JL Cadet - Brain research reviews, 2009 - Elsevier
Methamphetamine (METH) is an illicit psychostimulant that is widely abused in the world.
Several lines of evidence suggest that chronic METH abuse leads to neurodegenerative …

Glutamatergic substrates of drug addiction and alcoholism

JT Gass, MF Olive - Biochemical pharmacology, 2008 - Elsevier
The past two decades have witnessed a dramatic accumulation of evidence indicating that
the excitatory amino acid glutamate plays an important role in drug addiction and …

The neurobiology of methamphetamine induced psychosis

JH Hsieh, DJ Stein, FM Howells - Frontiers in human neuroscience, 2014 - frontiersin.org
Chronic methamphetamine abuse commonly leads to psychosis, with positive and cognitive
symptoms that are similar to those of schizophrenia. Methamphetamine induced psychosis …

Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons

T Steinkellner, V Zell, ZJ Farino… - The Journal of …, 2018 - Am Soc Clin Investig
Parkinson's disease is characterized by the loss of dopamine (DA) neurons in the substantia
nigra pars compacta (SNc). DA neurons in the ventral tegmental area are more resistant to …

Changes in the prefrontal glutamatergic and parvalbumin systems of mice exposed to unpredictable chronic stress

R Shepard, L Coutellier - Molecular neurobiology, 2018 - Springer
The prefrontal cortex (PFC) is highly sensitive to the effects of stress, a known risk factor of
mood disorders including anxiety and depression. Abnormalities in PFC functioning have …

Epigenetic effects induced by methamphetamine and methamphetamine‐dependent oxidative stress

F Limanaqi, S Gambardella, F Biagioni… - Oxidative medicine …, 2018 - Wiley Online Library
Methamphetamine is a widely abused drug, which possesses neurotoxic activity and
powerful addictive effects. Understanding methamphetamine toxicity is key beyond the field …

Molecular, structural, functional, and pharmacological sites for vesicular glutamate transporter regulation

N Pietrancosta, M Djibo, S Daumas… - Molecular …, 2020 - Springer
Vesicular glutamate transporters (VGLUTs) control quantal size of glutamatergic
transmission and have been the center of numerous studies over the past two decades …

Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death

H Nakajima, W Amano, T Kubo, A Fukuhara… - Journal of Biological …, 2009 - ASBMB
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) 2 2The abbreviations used are:
GAPDHglyceraldehyde-3-phosphate dehydrogenaseNOR3 (±)-(E)-4-ethyl-2-[(E) …

Melatonin reverts methamphetamine-induced learning and memory impairments and hippocampal alterations in mice

N Veschsanit, JL Yang, S Ngampramuan, K Viwatpinyo… - Life sciences, 2021 - Elsevier
Aims Methamphetamine (METH) has become a major public health problem because of its
abuse and profound neurotoxic effects, causing alterations in brain structure and function …

Mephedrone, an abused psychoactive component of 'bath salts' and methamphetamine congener, does not cause neurotoxicity to dopamine nerve endings of the …

M Angoa‐Pérez, MJ Kane… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 120, 1097–1107. Abstract Mephedrone (4‐methylmethcathinone) is a
β‐ketoamphetamine with close structural analogy to substituted amphetamines and …