Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte‐mediated glutamate clearance in the dCA1

T He, N Li, P Shi, X Xu, J Nie, X Lu, P Yu… - Addiction …, 2022 - Wiley Online Library
Methamphetamine (METH) elicits endogenous glutamate (Glu) in the brain, which could
partially explain METH‐induced memory deficits. Here, we investigated the therapeutic …

Metabolic abnormalities in abstinent methamphetamine dependent subjects

N Sailasuta, O Abulseoud… - Substance abuse …, 2010 - journals.sagepub.com
Introduction Chronic methamphetamine use results in persistent neuropsychological deficits
in abstinent methamphetamine dependent (AMD) subjects. We examined the hypothesis …

The orexin-1 receptor antagonist SB-334867 decreases sympathetic responses to a moderate dose of methamphetamine and stress

DE Rusyniak, DV Zaretsky, MV Zaretskaia… - Physiology & …, 2012 - Elsevier
We recently discovered that inhibiting neurons in the dorsomedial hypothalamus (DMH)
attenuated hyperthermia, tachycardia, hypertension, and hyperactivity evoked by the …

Deletion of VGLUT2 in midbrain dopamine neurons attenuates dopamine and glutamate responses to methamphetamine in mice

H Shen, K Chen, RAM Marino, RA McDevitt… - Pharmacology …, 2021 - Elsevier
Methamphetamine (METH) is a highly addictive psychostimulant. The continuous use of
METH may lead to its abuse and neurotoxicity that have been associated with METH …

[HTML][HTML] Glutamate-Mediated Excitotoxicity in the Pathogenesis and Treatment of Neurodevelopmental and Adult Mental Disorders

N Nicosia, M Giovenzana, P Misztak… - International Journal of …, 2024 - mdpi.com
Glutamate is the main excitatory neurotransmitter in the brain wherein it controls cognitive
functional domains and mood. Indeed, brain areas involved in memory formation and …

[HTML][HTML] Changes in glutamate/NMDA receptor subunit 1 expression in rat brain after acute and subacute exposure to methamphetamine

W Kerdsan, S Thanoi… - BioMed Research …, 2009 - Wiley Online Library
Methamphetamine (METH) is a psychostimulant drug of abuse that produces long‐term
behavioral changes including behavioral sensitization, tolerance, and dependence. METH …

Changes in VGLUT1 and VGLUT2 expression in rat dorsal root ganglia and spinal cord following spared nerve injury

HS Wang, G Yu, ZT Wang, SP Yi, RB Su… - Neurochemistry …, 2016 - Elsevier
Disturbance of glutamate homeostasis is a well-characterized mechanism of neuropathic
pain. Vesicular glutamate transporters (VGLUTs) determine glutamate accumulation in …

Chicago sky blue 6B, a vesicular glutamate transporters inhibitor, attenuates methamphetamine-induced hyperactivity and behavioral sensitization in mice

Z He, L Yan, Z Yong, Z Dong, H Dong, Z Gong - Behavioural brain research, 2013 - Elsevier
Several lines of evidence demonstrate that glutamatergic system plays an important role in
drug addiction. The present study was designed to investigate the effects of Chicago sky …

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity

MY Aksenov, MV Aksenova, CF Mactutus… - Journal of Neuroimmune …, 2012 - Springer
The interactive effects of HIV-1 infection and methamphetamine (METH) abuse in producing
cognitive dysfunction represent a serious medical problem; however, the neural …

Drug abuse, brain calcification and glutamate-induced neurodegeneration

MJ Rodríguez, M Pugliese… - Current Drug Abuse …, 2009 - ingentaconnect.com
Positive and negative reinforcing systems are part of the mechanism of drug dependence.
Drugs with abuse potential may change the manner of response to negative emotional …