Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …

In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …

The current understanding of nanoparticle–protein interactions indicates that they rapidly
adsorb proteins upon introduction into a living organism. The formed protein corona …

Poor water solubility and low bioavailability of active pharmaceutical ingredients (APIs) are
major causes of friction in the pharmaceutical industry and represent a formidable hurdle for …

For decades, nanomedicines have been reported as a potential means to overcome the
limitations of conventional drug delivery systems by reducing side effects, toxicity and the …

Over the past few decades, the complexity of molecular entities being advanced for
therapeutic purposes has continued to evolve. A main propellent fueling innovation is the …

Modifying biological agents with polymers such as polyethylene glycol (PEG) has
demonstrated clinical benefits; however, post-market surveillance of PEGylated derivatives …

Polymerization-induced self-assembly (PISA) and crystallization-driven self-assembly
(CDSA) techniques have emerged as powerful approaches to produce a broad range of …

Using polyethylene glycol (PEG) to functionalize liposomes improves their stealth properties
and stability in blood. However, PEG is known to induce the accelerated blood clearance …

The clinical success of polypeptides as polymeric drugs, covered by the umbrella term
“polymer therapeutics,” combined with related scientific and technological breakthroughs …