5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Serotonin is perhaps best known as a neurotransmitter that modulates neural activity and a
wide range of neuropsychological processes, and drugs that target serotonin receptors are …

Ayahuasca is a hallucinogenic botanical beverage originally used by indigenous
Amazonian tribes in religious ceremonies and therapeutic practices. While ethnobotanical …

BACKGROUND: We evaluated the magnitude of the reported associations between
amygdala activation and the serotonin transporter gene linked polymorphic region (5 …

Carcinoid heart disease was one of the first valvular pathologies studied in molecular detail,
and early research identified serotonin produced by oncogenic enterochromaffin cells as the …

The serotonin (5-HT) system is generally considered as a single modulatory system, with
broad and diffuse projections. However, accumulating evidence points to the existence of …

Discovered and crystallized over sixty years ago, serotonin's important functions in the brain
and body were identified over the ensuing years by neurochemical, physiological and …

Autism is a developmental disorder defined by the presence of a triad of communication,
social and stereo typical behavioral characteristics with onset before 3 years of age. In spite …

Neuroimaging with positron emission tomography (PET) is the most powerful tool for
understanding pharmacology, neurochemistry, and pathology in the living human brain. This …

Neuronal communication plays an essential role in the propagation of information in the
brain and requires a precisely orchestrated connectivity between neurons. Synaptic …