Cardiac PET imaging for the detection and monitoring of coronary artery disease and microvascular health

TH Schindler, HR Schelbert, A Quercioli… - JACC: Cardiovascular …, 2010 - jacc.org
Positron emission tomography (PET) myocardial perfusion imaging in concert with tracer-
kinetic modeling affords the assessment of regional myocardial blood flow (MBF) of the left …

Cardiac PET perfusion tracers: current status and future directions

J Maddahi, RRS Packard - Seminars in nuclear medicine, 2014 - Elsevier
PET myocardial perfusion imaging (MPI) is increasingly being used for noninvasive
detection and evaluation of coronary artery disease. However, the widespread use of PET …

Patient-centered imaging

EG DePuey, JJ Mahmarian, TD Miller, AJ Einstein… - 2012 - Elsevier
The continued success of nuclear cardiology demands ongoing re-evaluation of imaging
practices to optimize patient care. The first element of this process is to accurately define …

Absolute quantitation of myocardial blood flow in human subjects with or without myocardial ischemia using dynamic flurpiridaz F 18 PET

RRS Packard, SC Huang, M Dahlbom… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of
analyzing coronary artery disease (CAD) but subject to the various shortcomings of …

Characterizing the transition from immune response to tissue repair after myocardial infarction by multiparametric imaging

A Hess, T Borchert, TL Ross, FM Bengel… - Basic Research in …, 2022 - Springer
Persistent inflammation following myocardial infarction (MI) precipitates adverse outcome
including acute ventricular rupture and chronic heart failure. Molecular imaging allows …

New SPECT and PET radiopharmaceuticals for imaging cardiovascular disease

OO Sogbein, M Pelletier-Galarneau… - BioMed research …, 2014 - Wiley Online Library
Nuclear cardiology has experienced exponential growth within the past four decades with
converging capacity to diagnose and influence management of a variety of cardiovascular …

Molecular imaging of early αvβ3 integrin expression predicts long-term left-ventricle remodeling after myocardial infarction in rats

HM Sherif, A Saraste, SG Nekolla, E Weidl… - Journal of Nuclear …, 2012 - Soc Nuclear Med
18F-galacto-RGD (18F-RGD) is a PET tracer binding to αvβ3 integrin receptors that are
upregulated after myocardial infarction (MI) as part of the healing process. We studied …

Simplified quantification of myocardial flow reserve with flurpiridaz F 18: validation with microspheres in a pig model

HM Sherif, SG Nekolla, A Saraste… - Journal of nuclear …, 2011 - Soc Nuclear Med
The novel PET flow tracer flurpiridaz F 18 shows high myocardial extraction and slow
washout. flurpiridaz F 18 PET data analysis with tracer kinetic modeling provides accurate …

Moving into the next era of PET myocardial perfusion imaging: introduction of novel 18F-labeled tracers

RA Werner, X Chen, SP Rowe, C Lapa… - … International Journal of …, 2019 - Springer
The heart failure epidemic continues to rise with coronary artery disease as one of its main
causes. Novel concepts for risk stratification to guide the referring cardiologist towards …

Cardiac PET/CT for the evaluation of known or suspected coronary artery disease

MF Di Carli, VL Murthy - Radiographics, 2011 - pubs.rsna.org
Positron emission tomography (PET) is increasingly being applied in the evaluation of
myocardial perfusion. Cardiac PET can be performed with an increasing variety of cyclotron …