[HTML][HTML] Insects: an underrepresented resource for the discovery of biologically active natural products
L Seabrooks, L Hu - Acta Pharmaceutica Sinica B, 2017 - Elsevier
Nature has been the source of life-changing and-saving medications for centuries. Aspirin,
penicillin and morphine are prime examples of Nature׳ s gifts to medicine. These discoveries …
penicillin and morphine are prime examples of Nature׳ s gifts to medicine. These discoveries …
The interplay between kinetics and thermodynamics in furan diels–alder chemistry for sustainable chemicals production
Biomass‐derived furanic platform molecules have emerged as promising building blocks for
renewable chemicals and functional materials. To this aim, the Diels–Alder (DA) …
renewable chemicals and functional materials. To this aim, the Diels–Alder (DA) …
[HTML][HTML] The emerging roles of arthropods and their metabolites in the green synthesis of metallic nanoparticles
Nanotechnology has remained relevant as a multifacet discipline, which cuts across different
areas of science and technology. Several successful attempts had been documented …
areas of science and technology. Several successful attempts had been documented …
In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis
Cancer stem cells (CSCs) play pivotal roles in cancer metastasis, and strategies targeting
cancer stemness may greatly reduce cancer metastasis and improve patients' survival. The …
cancer stemness may greatly reduce cancer metastasis and improve patients' survival. The …
[HTML][HTML] Direct Diels–Alder reactions of furfural derivatives with maleimides
The Diels–Alder (DA) reaction of furans is a versatile tool in synthetic organic chemistry and
in the production of sustainable building blocks and smart materials. Numerous …
in the production of sustainable building blocks and smart materials. Numerous …
[HTML][HTML] Furoic acid and derivatives as atypical dienes in Diels–Alder reactions
The furan Diels–Alder (DA) cycloaddition reaction has become an important tool in green
chemistry, being central to the sustainable synthesis of many chemical building blocks. The …
chemistry, being central to the sustainable synthesis of many chemical building blocks. The …
Overview of cantharidin and its analogues
G Wang, J Dong, L Deng - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: Cantharidin has been categorized as highly toxicant in Chinese medicine. But
cantharidin can efficiently treat different types of diseases, such as molluscum contagiosum …
cantharidin can efficiently treat different types of diseases, such as molluscum contagiosum …
[HTML][HTML] Efficient route for the construction of polycyclic systems from bioderived HMF
The first synthesis of tricyclic compounds from biobased 5-hydroxymethylfurfural (HMF) is
described. The Diels–Alder reaction was used to implement the transition from HMF to a non …
described. The Diels–Alder reaction was used to implement the transition from HMF to a non …
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases
Background Fusion of DNA methyltransferase domains to the nuclease-deficient clustered
regularly interspaced short palindromic repeat (CRISPR) associated protein 9 (dCas9) has …
regularly interspaced short palindromic repeat (CRISPR) associated protein 9 (dCas9) has …
Targeting cancer cell mitochondria as a therapeutic approach: recent updates
Mitochondria play a key role in ATP generation, redox homeostasis and regulation of
apoptosis. Due to the essential role of mitochondria in metabolism and cell survival …
apoptosis. Due to the essential role of mitochondria in metabolism and cell survival …