Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Multiple biological, behavioural and genetic determinants or correlates of obesity have been
identified to date. Genome-wide association studies (GWAS) have contributed to the …

Background We aimed to identify the molecular mechanisms behind curcumin's therapeutic
benefits for metabolic syndrome (MetS) and its components. Methods The Comparative …

Spexin (SPX, NPQ) is a novel peptide involved in the regulation of energy metabolism. SPX
inhibits food intake and reduces body weight. In obese humans, SPX is the most down …

Background and aims Galanin is a naturally occurring peptide that plays a critical role in
regulating inflammation and energy metabolism, with expression in the liver. The exact …

Stressful life events and chronic stress are implicated in the development of depressive
disorder in humans. Neuropeptide Y (NPY) and galanin have been shown to modulate the …

Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …

The rapid increase in the prevalence of overweight and obesity is becoming an important
health problem. Overweight and obesity may cause several metabolic complications …

Pain and obesity, as well as their associated impairments, are major health concerns.
Understanding the relationship between the two is the focus of a growing body of research …

The increasing prevalence of type 2 diabetes mellitus with its high morbidity and mortality
becomes an important health problem. The multifactorial etiology of type 2 diabetes mellitus …