Cancer immunotherapy, such as immune checkpoint blockade (ICB), has emerged as a
groundbreaking approach for effective cancer treatment. Despite its considerable potential …

Ferroptosis differs from traditional cell death mechanisms like apoptosis, necrosis, and
autophagy, primarily due to its reliance on iron metabolism and the loss of glutathione …

Current research in cancer therapy focuses on personalized therapies, through
nanotechnology‐based targeted drug delivery systems. Particularly, controlled drug release …

Photodynamic therapy (PDT) and ferroptosis show significant potential in tumor treatment.
However, their therapeutic efficacy is often hindered by the oxygen-deficient tumor …

Drug resistance is currently one of the biggest challenges in cancer treatment. With the
deepening understanding of drug resistance, various mechanisms have been revealed …

Liver cancer is the second leading cause of cancer-related death worldwide. However,
treatment options, including surgical resection, transplantation, and molecular drug …

Ferroptosis, a recently identified type of non-apoptotic cell death, triggers the elimination of
cells in the presence of lipid peroxidation and in an iron-dependent manner. Indeed …

Background Sorafenib resistance is becoming increasingly common and disadvantageous
for hepatocellular carcinoma (HCC) treatment. Ferroptosis is an iron dependent …

Oral squamous cell carcinoma (OSCC) is a crucial public health problem, accounting for
approximately 2% of all cancers globally and 90% of oral malignancies over the world …

Lipid droplets (LDs), as primary cellular energy storage organelles, play essential roles not
only in energy conservation but also in inflammatory responses, apoptosis, and the …