The advent of optogenetic tools has had a profound impact on modern neuroscience
research, revolutionizing our understanding of the brain. These tools offer a remarkable …

Microglia are the resident immune cells of the central nervous system, undertaking
surveillance role and reacting to brain homeostasis and neurological diseases. Recent …

Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …

Hypersynchronous (HYP) seizure onset is one of the frequently observed seizure-onset
patterns in temporal lobe epileptic animals and patients, often accompanied by hippocampal …

Catamenial epilepsy, defined as a periodicity of seizure exacerbation during the menstrual
cycle, affects up to 70% of epileptic women. Seizures in these patients are often non …

In medication-resistant epilepsy, the goal of epilepsy surgery is to make a patient seizure
free with a resection/ablation that is as small as possible to minimize morbidity. The standard …

There is active debate regarding how GABAergic function changes during seizure initiation
and propagation, and whether interneuronal activity drives or impedes the pathophysiology …

Preface to the special issue neural circuit mechanisms in epilepsy and targeted therapeutics. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …