Metal compounds against neglected tropical diseases
Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …
Organization (WHO) are limited by one or more of the following: the development of drug …
Ferroquine and its derivatives: new generation of antimalarial agents
Malaria has been teasing human populations from a long time. Presently, several classes of
antimalarial drugs are available in market, but the issues of toxicity, lower efficacy and the …
antimalarial drugs are available in market, but the issues of toxicity, lower efficacy and the …
Organometallic compounds in drug discovery: Past, present and future
YC Ong, G Gasser - Drug Discovery Today: Technologies, 2020 - Elsevier
In this review, we present an overview of some of the medicinally-relevant organometallic
drugs that have been used in the past or that are currently in clinical trials as well as an …
drugs that have been used in the past or that are currently in clinical trials as well as an …
Homology Modelling and Molecular Docking Studies of Selected Substituted Benzo[d]imidazol-1-yl)methyl)benzimidamide Scaffolds on Plasmodium falciparum …
Plasmodium falciparum adenylosuccinate lyase (Pf ADSL) is an important enzyme in purine
metabolism. Although several benzimidazole derivatives have been commercially …
metabolism. Although several benzimidazole derivatives have been commercially …
Design of prospective antiparasitic metal-based compounds including selected organometallic cores
D Gambino, L Otero - Inorganica Chimica Acta, 2018 - Elsevier
A group of seventeen communicable and poverty-related diseases are considered
neglected by the World Health Organization due to the restricted development of diagnostic …
neglected by the World Health Organization due to the restricted development of diagnostic …
Antiprotozoal activity of medicinal plants used by Iquitos-Nauta road communities in Loreto (Peru)
P Vásquez-Ocmín, S Cojean, E Rengifo… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance In the Peruvian Amazon, the use of medicinal
plants is a common practice. However, there is few documented information about the …
plants is a common practice. However, there is few documented information about the …
[HTML][HTML] Synthesis and biological activity of novel oxazinyl flavonoids as antiviral and anti-phytopathogenic fungus agents
Y Ma, L Wang, A Lu, W Xue - Molecules, 2022 - mdpi.com
A series of oxazinyl flavonoids were synthesized on the basis of flavone. The structures of all
target compounds were characterized by 1H NMR, 13C NMR, and HRMS. The effect of the …
target compounds were characterized by 1H NMR, 13C NMR, and HRMS. The effect of the …
Design, synthesis and biological evaluation of novel hydroxy-phenyl-1H-benzimidazoles as radical scavengers and UV-protective agents
A Bino, A Baldisserotto, E Scalambra… - Journal of Enzyme …, 2017 - Taylor & Francis
An ever-increasing incidence of skin neoplastic diseases is registered. Therefore, it is
important to protect the skin from the UV radiation that reaches the epidermis and dermis but …
important to protect the skin from the UV radiation that reaches the epidermis and dermis but …
Remarkable Brain Penetration of Cyclopentadienyl M(CO)3+ (M = 99mTc, Re) Derivatives of Benzothiazole and Benzimidazole Paves the Way for Their Application …
The synthesis and evaluation of three novel 99mTc complexes (99m Tc-1–3) and their
corresponding Re complexes (Re-1–3), in which the phenyl ring of 2-phenylbenzothiazole …
corresponding Re complexes (Re-1–3), in which the phenyl ring of 2-phenylbenzothiazole …
Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells
Searching for a more effective chemotherapy for the treatment of Human African
trypanosomiasis, the disease caused by the parasite Trypanosoma brucei, and cancer, in …
trypanosomiasis, the disease caused by the parasite Trypanosoma brucei, and cancer, in …